Overview

  • Product name

  • Description

    Rabbit polyclonal to THEA
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human THEA aa 18-238.
    Sequence:

    R TSRKSALRAG NDSAMADGEG YRNPTEVQMS QLVLPCHTNQ RGELSVGQLL KWIDTTACLS AERHAGCPCV TASMDDIYFE HTISVGQVVN IKAKVNRAFN SSMEVGIQVA SEDLCSEKQW NVCKALATFV ARREITKVKL KQITPRTEEE KMEHSVAAER RRMRLVYADT IKDLLANCAI QGDLESRDCS RMVPAEKTRV ESVELVLPPH ANHQGNTF


    Database link: Q8WXI4

  • Positive control

    • 293T, A431, Jurkat cells
  • General notes

     This product was previously labelled as ACOT11

     

Properties

Applications

Our Abpromise guarantee covers the use of ab153835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 68 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates.
  • Tissue specificity

    Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue.
  • Sequence similarities

    Contains 2 acyl coenzyme A hydrolase domains.
    Contains 1 START domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • ACO11_HUMAN antibody
    • ACOT 11 antibody
    • ACOT11 antibody
    • Acyl CoA thioester hydrolase 11 antibody
    • Acyl CoA thioesterase 11 antibody
    • Acyl coenzyme A thioesterase 11 antibody
    • Acyl-CoA thioester hydrolase 11 antibody
    • Acyl-CoA thioesterase 11 antibody
    • Acyl-coenzyme A thioesterase 11 antibody
    • Adipose associated thioesterase antibody
    • Adipose-associated thioesterase antibody
    • BFIT 1 antibody
    • BFIT 2 antibody
    • BFIT antibody
    • BFIT1 antibody
    • BFIT2 antibody
    • Brown fat inducible thioesterase antibody
    • Brown fat-inducible thioesterase antibody
    • KIAA0707 antibody
    • OTTHUMP00000046722 antibody
    • StAR related lipid transfer (START) domain containing 14 antibody
    • STARD 14 antibody
    • STARD14 antibody
    • START domain containing 14 antibody
    • THEA antibody
    • THEM 1 antibody
    • THEM1 antibody
    • Thioesterase adipose associated antibody
    • Thioesterase superfamily member 1 antibody
    see all

Images

  • Anti-THEA antibody (ab153835) at 1/1000 dilution + Jurkat 30µg whole cell lysate

    Predicted band size: 68 kDa



    7.5% SDS PAGE
  • Immunofluorescence analysis of methanol-fixed A431 using ab153835 antibody at 1/200 dilution. The bottom image shows counterstaining with a nuclear dye.

References

This product has been referenced in:

  • Hung JY  et al. Overexpression and proliferation dependence of acyl-CoA thioesterase 11 and 13 in lung adenocarcinoma. Oncol Lett 14:3647-3656 (2017). Read more (PubMed: 28927126) »
See 1 Publication for this product

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