Key features and details
- Rabbit polyclonal to THEM4
- Suitable for: ICC/IF, IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-THEM4 antibody
DescriptionRabbit polyclonal to THEM4
Tested applicationsSuitable for: ICC/IF, IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
18 amino acid synthetic peptide designed near the center of Human THEM4 (NP_444283).
- Human liver tissue / tissue lysate.
Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106435 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|IHC-P||Use a concentration of 2.5 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 27 kDa.|
FunctionAccording to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
Tissue specificityExpressed predominantly in skeletal muscle, testis, uterus, brain and kidney. Down-regulated in glioblastoma or glioma compared to non-neoplastic brain due to promoter hypermethylation.
Cellular localizationCell membrane. Cell projection > ruffle membrane. Cytoplasm.
- Information by UniProt
- Acyl CoA thioesterase THEM4 antibody
- Acyl coenzyme A thioesterase THEM4 antibody
- C terminal modulator protein antibody
Lane 1 : Anti-THEM4 antibody (ab106435) at 1 µg/ml
Lane 2 : Anti-THEM4 antibody (ab106435) at 2 µg/ml
All lanes : Human liver tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 27 kDa
Immunofluorescence of THEM4 in Human liver tissue with ab106435 at 20 ug/mL.
ab106435 at 2.5µg staining THEM4 in paraffin embedded Human liver tissue by immunohistochemistry.
ab106435 has been referenced in 1 publication.
- Li J et al. Age-Related Upregulation of Carboxyl Terminal Modulator Protein Contributes to the Decreased Brain Ischemic Tolerance in Older Rats. Mol Neurobiol 55:6145-6154 (2018). PubMed: 29250714