Recombinant
RabMAb

Recombinant Anti-Themis antibody [EPR7353] - BSA and Azide free (ab248177)

Overview

  • Product name

    Anti-Themis antibody [EPR7353] - BSA and Azide free
    See all Themis primary antibodies
  • Description

    Rabbit monoclonal [EPR7353] to Themis - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC, Flow Cyt, IP, WBmore details
    Unsuitable for: IHC-P
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Themis aa 200-300. The exact sequence is proprietary.
    Database link: Q8N1K5

  • General notes

    Ab248177 is the carrier-free version of ab126771. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab248177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 73 kDa.
  • Application notes
    Is unsuitable for IHC-P.
  • Target

    • Function

      Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
    • Sequence similarities

      Belongs to the themis family.
    • Post-translational
      modifications

      Phosphorylated on Tyr residues quickly after TCR stimulation.
    • Cellular localization

      Cytoplasm. Nucleus.
    • Information by UniProt
    • Database links

    • Alternative names

      • C6orf190 antibody
      • C6orf207 antibody
      • MGC163388 antibody
      • Protein THEMIS antibody
      • SIGNALING PHOSPHOPROTEIN SPECIFIC FOR T CELLS antibody
      • SPOT antibody
      • THEMIS antibody
      • THMS1_HUMAN antibody
      • Thymocyte expressed molecule involved in selection antibody
      • Thymocyte selection associated antibody
      • Thymocyte selection pathway associated antibody
      • Thymocyte-expressed molecule involved in selection antibody
      • TSEPA antibody
      see all

    References

    ab248177 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab248177.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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