Product nameAnti-Themis antibody - N-terminal
See all Themis primary antibodies
DescriptionRabbit polyclonal to Themis - N-terminal
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat
Synthetic peptide (Human) corresponding to a sequence from the N-terminal region of Human Themis.
- Mouse spleen tissue lysate; K562 cell lysate
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: 50% Glycerol, 0.1% BSA, 48% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab157811 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Detects a band of approximately 72 kDa (predicted molecular weight: 73 kDa).|
FunctionPlays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
Sequence similaritiesBelongs to the themis family.
modificationsPhosphorylated on Tyr residues quickly after TCR stimulation.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- C6orf190 antibody
- C6orf207 antibody
- MGC163388 antibody
Lanes 1 & 5 : Anti-Themis antibody - N-terminal (ab157811) at 1/2000 dilution
Lanes 2 & 6 : Anti-Themis antibody - N-terminal (ab157811) at 1/1000 dilution
Lanes 3-4 & 7-8 : Anti-Themis antibody - N-terminal (ab157811) at 1/500 dilution
Lanes 1-3 : Mouse spleen tissue lysate
Lane 4 : Mouse spleen tissue lysate with blocking peptide
Lanes 5-7 : K562 cell lysate
Lane 8 : K562 cell lysate with blocking peptide
Predicted band size: 73 kDa
ab157811 has not yet been referenced specifically in any publications.