Thioflavin T, Fluorescent cell-permeable amyloid binding benzothiazole salt (ab120751)

Overview

  • Product name

    Thioflavin T, Fluorescent cell-permeable amyloid binding benzothiazole salt
  • Description

    Fluorescent cell-permeable amyloid binding benzothiazole salt
  • Biological description

    Fluorescent cell-permeable amyloid binding benzothiazole salt. Dye used to visualise stacked β sheets in vitro and in vivo. Binding induces a shift in excitation maximum (385 nm to 450 nm) and emission maximum (445 nm to 482 nm). Highly soluble in water. Limited ability to cross the blood-brain barrier.
  • Purity

    > 97%
  • CAS Number

    2390-54-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Biancalana M & Koide S Molecular mechanism of Thioflavin-T binding to amyloid fibrils. Biochim Biophys Acta 1804:1405-12 (2010). Read more (PubMed: 20399286) »
  • Darghal N  et al. Mechanism of thioflavin T accumulation inside cells overexpressing P-glycoprotein or multidrug resistance-associated protein: role of lipophilicity and positive charge. Biochem Biophys Res Commun 343:623-9 (2006). Read more (PubMed: 16554036) »
See all 6 Publications for this product

Customer reviews and Q&As

Question
Answer

Thioflavin T has widely been used in frozen tissue so this product should work in frozen tissue.

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