Overview

  • Product name

    Anti-Thrombin-Antithrombin Complex antibody [22]
  • Description

    Mouse monoclonal [22] to Thrombin-Antithrombin Complex
  • Host species

    Mouse
  • Tested applications

    Suitable for: Sandwich ELISA, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Other Immunogen Type corresponding to Human Thrombin-Antithrombin Complex. Thrombin-antithrombin (TAT) complexes.

Properties

Applications

Our Abpromise guarantee covers the use of ab191378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

Target

  • Relevance

    Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Antithrombin: Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. Antithrombin inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • antithrombin III antibody
    • AT3 antibody
    • AT3D antibody
    • ATIII antibody
    • coagulation factor II (thrombin) antibody
    • F2 antibody
    • PRO0309 antibody
    • prothrombin antibody
    • prothrombin B chain antibody
    • PT antibody
    • RPRGL2 antibody
    • serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1 antibody
    • serine protease antibody
    • serine-cysteine proteinase inhibitor clade C member 1 antibody
    • serpin C1 antibody
    • serpin peptidase inhibitor, clade C (antithrombin), member 1 antibody
    • SERPINC1 antibody
    • TAT antibody
    • THPH1 antibody
    • THPH7 antibody
    see all

Images

  • Immunohistochemistry staining of Thrombin-Antithrombin Complex in human tonsil tissue with ab191378 (1/30). 

References

ab191378 has not yet been referenced specifically in any publications.

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