• Product name
    Anti-Thrombin Receptor antibody
    See all Thrombin Receptor primary antibodies
  • Description
    Rabbit polyclonal to Thrombin Receptor
  • Host species
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Baboon
  • Immunogen

    Synthetic peptide within Human Thrombin Receptor aa 1-100. The exact sequence is proprietary.
    Database link: P25116
    (Peptide available as ab65987)

  • Positive control
    • KNRK cells, Pancreatic tissue.



Our Abpromise guarantee covers the use of ab32611 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 52 kDa (predicted molecular weight: 47 kDa).
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.


  • Function
    High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
  • Tissue specificity
    Platelets and vascular endothelial cells.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
    Phosphorylated; probably mediating desensitization prior to the uncoupling and internalization of the receptor.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CF2R antibody
    • Coagulation factor II (thrombin) receptor antibody
    • Coagulation factor II receptor antibody
    • F2R antibody
    • HTR antibody
    • PAR 1 antibody
    • PAR-1 antibody
    • PAR1 antibody
    • PAR1_HUMAN antibody
    • Protease activated receptor 1 antibody
    • Proteinase activated receptor 1 antibody
    • Proteinase-activated receptor 1 antibody
    • Thrombin receptor antibody
    • TR antibody
    see all


  • Anti-Thrombin Receptor antibody (ab32611) at 1 µg/ml + Human Platelet (Human adult normal cell line) Whole Cell Lysate at 10 µg

    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size: 47 kDa
    Observed band size: 52 kDa (why is the actual band size different from the predicted?)
    Additional bands at: 87 kDa. We are unsure as to the identity of these extra bands.

    Exposure time: 12 minutes

    Thrombin Receptor contains a number of potential glycosylation sites (SwissProt) which may explain its migration at a higher molecular weight than predicted.
  • This image shows human pancreas stained with ab32611.


This product has been referenced in:
  • Bushi D  et al. A Linear Temporal Increase in Thrombin Activity and Loss of Its Receptor in Mouse Brain following Ischemic Stroke. Front Neurol 8:138 (2017). WB ; Mouse . Read more (PubMed: 28443061) »
  • Chen KD  et al. Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma. Cell Death Dis 5:e1244 (2014). WB ; Human . Read more (PubMed: 24853422) »

See all 4 Publications for this product

Customer reviews and Q&As

Thank you for contacting us in regards to the Anti-Thrombin Receptor antibody (ab32611) and sorry for the late reply.

As discussed over the phone, I have enquired as to whether we are able to provide the immunising peptide used to raise the a...

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Thank you for contacting us.

The Uniprot http://www.uniprot.org/uniprot/P25116 database shows, the active part of protein "human Proteinase-activated receptor 1" has amino acid sequence between 42-425, so antibodies specific to this ...

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