Overview

  • Product name

    Anti-Thromboxane synthase antibody
    See all Thromboxane synthase primary antibodies
  • Description

    Rabbit polyclonal to Thromboxane synthase
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human Thromboxane synthase aa 354-533 (C terminal).
    Database link: P24557

  • Positive control

    • A549, HT-29, U937 and H460 cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab187176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 61 kDa.
IHC-P 1/50 - 1/200.

Target

  • Tissue specificity

    Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.
  • Involvement in disease

    Defects in TBXAS1 are the cause of Ghosal hematodiaphyseal dysplasia (GHDD) [MIM:231095]. GHDD is a rare autosomal recessive disorder characterized by increased bone density with predominant diaphyseal involvement and aregenerative corticosteroid-sensitive anemia. Aregenerative anemia is characterized by bone marrow failure, so that functional marrow cells are regenerated slowly or not at all.
    Defects in TBXAS1 are the cause of thromboxane synthetase deficiency (TBXAS1 deficiency) [MIM:274180]. It is characterized by hemorrhagic diathesis.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • BDPLT14 antibody
    • CYP5 antibody
    • CYP5A1 antibody
    • Cytochrome P450 5A1 antibody
    • Cytochrome P450, family 5, subfamily A, polypeptide 1 antibody
    • FLJ52771 antibody
    • GHOSAL antibody
    • Platelet cytochrome P450 subfamily V antibody
    • Tbxas1 antibody
    • THAS antibody
    • THAS_HUMAN antibody
    • Thromboxane A synthase 1 (platelet) antibody
    • Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) antibody
    • Thromboxane A synthase 1 antibody
    • Thromboxane A synthase 1 platelet cytochrome P450 subfamily V antibody
    • Thromboxane-A synthase antibody
    • TS antibody
    • TXA synthase antibody
    • TXAS antibody
    • TXS antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse lung tissue labelling Thromboxane synthase with ab187176 at 1/200. Magnification: 400x.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human thyroid cancer tissue labelling Thromboxane synthase with ab187176 at 1/200. Magnification: 400x.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human endometrial cancer tissue labelling Thromboxane synthase with ab187176 at 1/200. Magnification: 400x.
  • All lanes : Anti-Thromboxane synthase antibody (ab187176) at 1/500 dilution

    Lane 1 : A549 cell extract
    Lane 2 : HT-29 cell extract
    Lane 3 : U937 cell extract
    Lane 4 : H460 cell extract

    Predicted band size: 61 kDa

References

ab187176 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab187176.
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