Overview

  • Product name

  • Description

    Goat polyclonal to THRSP
  • Host species

    Goat
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human THRSP aa 87-100 (internal sequence) (Cysteine residue). (NP_003242.1)
    Sequence:

    (c)SEENGTAETEEVED


    Database link: Q92748

  • Positive control

    • FC: A431 cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab239216 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use a concentration of 10 µg/ml.

Target

  • Function

    Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
  • Tissue specificity

    Mainly expressed in tissues that synthesize triglycerides.
  • Sequence similarities

    Belongs to the SPOT14 family.
  • Cellular localization

    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Lpgp antibody
    • LPGP1 antibody
    • MGC21659 antibody
    • OTTHUMP00000233866 antibody
    • S14 antibody
    • S14 protein antibody
    • SPOT 14 antibody
    • Spot 14 protein antibody
    • SPOT14 antibody
    • SPOT14 homolog antibody
    • Thrsp antibody
    • THRSP_HUMAN antibody
    • Thyroid hormone inducible hepatic protein antibody
    • Thyroid hormone responsive (SPOT14 homolog rat) antibody
    • Thyroid hormone responsive antibody
    • Thyroid hormone responsive protein antibody
    • Thyroid hormone responsive SPOT14 antibody
    • Thyroid hormone-inducible hepatic protein antibody
    see all

Images

  • Flow cytometric analysis of paraformaldehyde fixed A431 (Human epidermoid carcinoma cell line) cells (blue line), permeabilized with 0.5% Triton. Primary incubation time 1 hour (10 µg/ml) followed by an Alexa-Fluor®488 secondary antibody (2 µg/ml).

    IgG control: Non-immunized goat IgG (black line) followed by an Alexa-Fluor®488 secondary antibody.

References

ab239216 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab239216.
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