Key features and details
- Mouse monoclonal [P-GF.44C] to Thymidine Phosphorylase
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-Thymidine Phosphorylase antibody [P-GF.44C]
See all Thymidine Phosphorylase primary antibodies
DescriptionMouse monoclonal [P-GF.44C] to Thymidine Phosphorylase
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant full length protein corresponding to Human Thymidine Phosphorylase.
Database link: P19971
- Human placenta tissue.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: 0.05% BSA, 99% PBS
Concentration information loading...
PurityProtein A/G purified
Purification notesab218381 is purified from Bioreactor Concentrate by Protein A/G.
Our Abpromise guarantee covers the use of ab218381 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
(for 30 minutes at RT)
FunctionMay have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro.
Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
PathwayPyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2.
Involvement in diseaseMitochondrial DNA depletion syndrome 1 (MTDPS1) [MIM:603041]: A multisystem disease associated with mitochondrial dysfunction. It is clinically characterized by onset between the second and fifth decades of life, ptosis, progressive external ophthalmoplegia, gastrointestinal dysmotility (often pseudoobstruction), diffuse leukoencephalopathy, cachexia, peripheral neuropathy, and myopathy. Note=The disease is caused by mutations affecting the gene represented in this entry.
Sequence similaritiesBelongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
- Information by UniProt
- ECGF 1 antibody
- ECGF antibody
- ECGF1 antibody
ab218381 has not yet been referenced specifically in any publications.