Anti-Thymidylate Synthase antibody - C-terminal (ab227774)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-Thymidylate Synthase antibody - C-terminal
See all Thymidylate Synthase primary antibodies -
Description
Rabbit polyclonal to Thymidylate Synthase - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Cow, Frog
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Immunogen
Synthetic peptide within Human Thymidylate Synthase aa 250 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P04818 -
Positive control
- IHC-P: Human colon carcinoma tissue.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.6
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab227774 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Primary antibody incubation for 30 minutes at room temperature. |
Target
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Function
Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. -
Pathway
Pyrimidine metabolism; dTTP biosynthesis. -
Sequence similarities
Belongs to the thymidylate synthase family. -
Cellular localization
Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane. - Information by UniProt
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Database links
- Entrez Gene: 507631 Cow
- Entrez Gene: 7298 Human
- Entrez Gene: 22171 Mouse
- Entrez Gene: 100347408 Rabbit
- Entrez Gene: 29261 Rat
- Omim: 188350 Human
- SwissProt: Q2TA32 Cow
- SwissProt: P04818 Human
see all -
Alternative names
- d TMP synthase antibody
- EC 2.1.1.45 antibody
- HsT422 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thymidylate Synthase antibody - C-terminal (ab227774)Formalin-fixed, paraffin-embedded human colon carcinoma tissue stained for Thymidylate Synthase using ab227774 at 1/100 dilution in immunohistochemical analysis.
Datasheets and documents
References
ab227774 has not yet been referenced specifically in any publications.
