Overview

  • Product name
  • Description
    Rabbit polyclonal to TIA1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Chicken, Guinea pig, Cow, Dog, Chimpanzee, Snake, Rhesus monkey, Chinese hamster, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 1-50 of Human TIA1 (NP_071505.2).

  • Positive control
    • 293T, HeLa and mouse TCMK-1 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab168837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2500. Predicted molecular weight: 43 kDa.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function
      Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
    • Sequence similarities
      Contains 3 RRM (RNA recognition motif) domains.
    • Cellular localization
      Cytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage.
    • Information by UniProt
    • Database links
    • Alternative names
      • Cytotoxic granule associated RNA binding protein 1 antibody
      • Cytotoxic granule associated RNA binding protein antibody
      • mTIA-1 antibody
      • Nucleolysin TIA 1 isoform p40 antibody
      • Nucleolysin TIA-1 isoform p40 antibody
      • Nucleolysin TIA1 isoform p40 antibody
      • p40 TIA 1 antibody
      • p40-TIA-1 (containing p15-TIA-1) antibody
      • p40-TIA-1 antibody
      • RNA binding protein TIA 1 antibody
      • RNA binding protein TIA1 antibody
      • RNA-binding protein TIA-1 antibody
      • T-cell-restricted intracellular antigen-1 antibody
      • TIA 1 antibody
      • TIA 1 cytotoxic granule associated RNA binding protein antibody
      • Tia antibody
      • TIA-1 antibody
      • TIA1 antibody
      • TIA1 cytotoxic granule associated RNA binding protein antibody
      • TIA1 cytotoxic granule associated RNA binding protein like 1 antibody
      • TIA1 protein antibody
      • TIA1_HUMAN antibody
      • TIAL1 antibody
      • TIAR antibody
      • WDM antibody
      see all

    Images

    • All lanes : Anti-TIA1 antibody (ab168837) at 1 µg/ml

      Lane 1 : Jurkat whole cell lysate
      Lane 2 : 293T whole cell lysate
      Lane 3 : HeLa whole cell lysate
      Lane 4 : TCMK-1 whole cell lysate

      Lysates/proteins at 50 µg per lane.

      Developed using the ECL technique.

      Predicted band size: 43 kDa


      Exposure time: 3 minutes

    References

    ab168837 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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