Anti-TIA1 antibody (ab205063)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-TIA1 antibody
See all TIA1 primary antibodies -
Description
Rabbit polyclonal to TIA1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human TIA1 aa 8-193. from Isoform 3: BC015944
Sequence:TLY VGNLSRDVTE ALILQLFSQI GPCKNCKMIM DTAGNDPYCF VEFHEHRHAA AALAAMNGRK IMGKEVKVNW ATTPSSQKKD TSSSTVVSTQ RSQDHFHVFV GDLSPEITTE DIKAAFAPFG RISDARVVKD MATGKSKGYG FVSFFNKWDA ENAIQQMGGQ WLGGRQIRTN WATRKPPAPK STY
Database link: P31483-3 -
Positive control
- K562 cell lysate. Human brain tissue.
Properties
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Form
Lyophilised:Reconstitute in 200ul sterile H2O. -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab205063 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/100 - 1/500. | |
| WB | 1/200 - 1/1000. Detects a band of approximately 43 kDa (predicted molecular weight: 43, 42, 24 kDa). |
Target
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Function
Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis. -
Sequence similarities
Contains 3 RRM (RNA recognition motif) domains. -
Cellular localization
Cytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage. - Information by UniProt
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Database links
- Entrez Gene: 7072 Human
- Omim: 603518 Human
- SwissProt: P31483 Human
- Unigene: 413123 Human
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Alternative names
- Cytotoxic granule associated RNA binding protein 1 antibody
- Cytotoxic granule associated RNA binding protein antibody
- mTIA-1 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TIA1 antibody (ab205063)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue labeling TIA1 with ab205063 at 1/100 dilution.
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Western blot - Anti-TIA1 antibody (ab205063)Anti-TIA1 antibody (ab205063) at 1/500 dilution + K562 cell lysate
Predicted band size: 43, 42, 24 kDa
References
ab205063 has not yet been referenced specifically in any publications.
