Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 0.01% BSA, 50% Glycerol
Aqueous buffered solution.
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab203078 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/100 - 1/1000. Predicted molecular weight: 125 kDa.|
|IHC-P||1/100 - 1/500.
(or 1/50 - 1/200 using a fluorescent secondary antibody).
FunctionTransmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
Tissue specificitySpecifically expressed in developing vascular endothelial cells.
Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily.
Contains 3 EGF-like domains.
Contains 3 fibronectin type-III domains.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.
modificationsPhosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2.
Cellular localizationCell membrane.
- Information by UniProt
- JKT 14 antibody
- JTK14 antibody
- TIE antibody
ab203078 has not yet been referenced specifically in any publications.