Overview

  • Product name

    Anti-TIGIT antibody [1G9] (Allophycocyanin)
    See all TIGIT primary antibodies
  • Description

    Mouse monoclonal [1G9] to TIGIT (Allophycocyanin)
  • Host species

    Mouse
  • Conjugation

    Allophycocyanin. Ex: 645nm, Em: 660nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • Mouse C57Bl/6 splenocytes.
  • General notes

    The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. 

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C. Store In the Dark.
  • Storage buffer

    pH: 7.2
    Preservative: 0.09% Sodium azide
    Constituents: 0.87% Sodium chloride, 0.1% Gelatin, 0.12% Monobasic dihydrogen sodium phosphate
  • Concentration information loading...
  • Purity

    Affinity purified
  • Purification notes

    ab210212 was purified from tissue culture supernatant via affinity chromatography
  • Clonality

    Monoclonal
  • Clone number

    1G9
  • Isotype

    IgG1
  • Light chain type

    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab210212 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Use 0.06 μg/test

Target

  • Function

    Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.
  • Tissue specificity

    Expressed at low levels on peripheral memory and regulatory CD4+ T cells and NK cells and is up-regulated following activation of these cells (at protein level).
  • Sequence similarities

    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Domain

    Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • DKFZp667A205 antibody
    • ENSMUSG00000071552 antibody
    • FLJ39873 antibody
    • RGD1563191 antibody
    • T cell immunoreceptor with Ig and ITIM domains antibody
    • TIGIT antibody
    • TIGIT_HUMAN antibody
    • V-set and immunoglobulin domain containing 9 antibody
    • V-set and immunoglobulin domain-containing protein 9 antibody
    • V-set and transmembrane domain containing 3 antibody
    • V-set and transmembrane domain-containing protein 3 antibody
    • VSIG9 antibody
    • VSTM3 antibody
    • Washington University cell adhesion molecule antibody
    • WUCAM antibody
    see all

Images

  • Flow cytometric analysis of C57Bl/6 splenocytes labeling TIGIT using ab210212 at 0.06 μg (right panel) or APC Mouse IgG1 control at 0.06 μg (left panel).

References

ab210212 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab210212.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up