Overview

  • Product name

  • Description

    Rabbit polyclonal to TIL/TLR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cyt, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to Human TIL/TLR1 conjugated to keyhole limpet haemocyanin.
    Database link: Q15399

  • Positive control

    • IHC-P: Rat brain tissue. Flow Cyt: Mouse splenocytes.

Properties

Applications

Our Abpromise guarantee covers the use of ab227379 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/20 - 1/100.
IHC-P 1/100 - 1/500.

Target

  • Function

    Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • Tissue specificity

    Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
  • Sequence similarities

    Belongs to the Toll-like receptor family.
    Contains 12 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • Cellular localization

    Cell membrane. Cytoplasmic vesicle > phagosome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD281 antibody
    • CD281 antigen antibody
    • KIAA0012 antibody
    • LPRS5 antibody
    • rsc786 antibody
    • TIL antibody
    • TIL. LPRS5 antibody
    • Tlr1 antibody
    • TLR1_HUMAN antibody
    • Toll (Drosophila) homolog antibody
    • Toll like receptor 1 antibody
    • Toll-like receptor 1 antibody
    • Toll/interleukin-1 receptor-like protein antibody
    see all

Images

  • Paraffin-embedded rat brain tissue stained for TIL/TLR1 using ab227379 at 1/200 dilution in immunohistochemical analysis. Detection: DAB staining.

  • Flow cytometric analysis of mouse splenocytes labeling TIL/TLR1 with ab227379 at 1/100 dilution followed by a PE conjugated secondary antibody (green) compared with an isotype control (orange), a secondary only control (light blue) and an unlabeled control (cells without incubation with primary antibody and secondary antibody) (blue).

References

ab227379 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab227379.
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