Key features and details
- Rabbit polyclonal to TIL/TLR1
- Suitable for: Flow Cyt, IHC-P
- Reacts with: Mouse, Rat
- Isotype: IgG
Product nameAnti-TIL/TLR1 antibody
See all TIL/TLR1 primary antibodies
DescriptionRabbit polyclonal to TIL/TLR1
Tested applicationsSuitable for: Flow Cyt, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat
Predicted to work with: Human
Synthetic peptide corresponding to Human TIL/TLR1 conjugated to keyhole limpet haemocyanin.
Database link: Q15399
- IHC-P: Rat brain tissue. Flow Cyt: Mouse splenocytes.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 1% BSA, 50% Glycerol
Aqueous buffered solution
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab227379 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||1/20 - 1/100.|
|IHC-P||1/100 - 1/500.|
FunctionParticipates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Tissue specificityUbiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
Sequence similaritiesBelongs to the Toll-like receptor family.
Contains 12 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain.
Cellular localizationCell membrane. Cytoplasmic vesicle > phagosome membrane.
- Information by UniProt
- CD281 antibody
- CD281 antigen antibody
- KIAA0012 antibody
Paraffin-embedded rat brain tissue stained for TIL/TLR1 using ab227379 at 1/200 dilution in immunohistochemical analysis. Detection: DAB staining.
Flow cytometric analysis of mouse splenocytes labeling TIL/TLR1 with ab227379 at 1/100 dilution followed by a PE conjugated secondary antibody (green) compared with an isotype control (orange), a secondary only control (light blue) and an unlabeled control (cells without incubation with primary antibody and secondary antibody) (blue).
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab227379 has not yet been referenced specifically in any publications.