Recombinant
RabMAb

Recombinant Anti-TIL/TLR1 antibody [EPR2075] - BSA and Azide free (ab239857)

Overview

  • Product name

    Anti-TIL/TLR1 antibody [EPR2075] - BSA and Azide free
    See all TIL/TLR1 primary antibodies
  • Description

    Rabbit monoclonal [EPR2075] to TIL/TLR1 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, Flow Cyt, IPmore details
    Unsuitable for: ICC or IHC-P
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human TIL/TLR1 aa 150-250 (extracellular). The exact sequence is proprietary.

  • General notes

    ab239857 is the carrier-free version of ab68158 This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    Ab239857 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab239857 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 90, 125 kDa (predicted molecular weight: 90 kDa).
Flow Cyt Use at an assay dependent concentration.

ab199376 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

IP Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for ICC or IHC-P.
  • Target

    • Function

      Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
    • Tissue specificity

      Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
    • Sequence similarities

      Belongs to the Toll-like receptor family.
      Contains 12 LRR (leucine-rich) repeats.
      Contains 1 LRRCT domain.
      Contains 1 TIR domain.
    • Cellular localization

      Cell membrane. Cytoplasmic vesicle > phagosome membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • CD281 antibody
      • CD281 antigen antibody
      • KIAA0012 antibody
      • LPRS5 antibody
      • rsc786 antibody
      • TIL antibody
      • TIL. LPRS5 antibody
      • Tlr1 antibody
      • TLR1_HUMAN antibody
      • Toll (Drosophila) homolog antibody
      • Toll like receptor 1 antibody
      • Toll-like receptor 1 antibody
      • Toll/interleukin-1 receptor-like protein antibody
      see all

    Images

    • Flow cytometric analysis of TIL/TLR1 in Daudi cells using ab68158 at 1/60 dilution (pink) or a rabbit IgG (green).

      This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab68158).

    References

    ab239857 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab239857.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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