Overview

  • Product name

    Anti-TIL/TLR1 antibody - N-terminal
    See all TIL/TLR1 primary antibodies
  • Description

    Rabbit polyclonal to TIL/TLR1 - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human TIL/TLR1 (N terminal). The exact sequence is proprietary.
    Database link: Q15399

  • Positive control

    • Mouse spleen lysate; mouse spleen tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab195439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 90 kDa.
IHC-P Use a concentration of 10 µg/ml.

Target

  • Function

    Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • Tissue specificity

    Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
  • Sequence similarities

    Belongs to the Toll-like receptor family.
    Contains 12 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • Cellular localization

    Cell membrane. Cytoplasmic vesicle > phagosome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD281 antibody
    • CD281 antigen antibody
    • KIAA0012 antibody
    • LPRS5 antibody
    • rsc786 antibody
    • TIL antibody
    • TIL. LPRS5 antibody
    • Tlr1 antibody
    • TLR1_HUMAN antibody
    • Toll (Drosophila) homolog antibody
    • Toll like receptor 1 antibody
    • Toll-like receptor 1 antibody
    • Toll/interleukin-1 receptor-like protein antibody
    see all

Images

  • Lane 1 : Anti-TIL/TLR1 antibody - N-terminal (ab195439) at 1 µg/ml
    Lane 2 : Anti-TIL/TLR1 antibody - N-terminal (ab195439) at 2 µg/ml
    Lane 3 : Anti-TIL/TLR1 antibody - N-terminal (ab195439) at 4 µg/ml

    All lanes : Mouse spleen lysate

    Predicted band size: 90 kDa

  • Immunohistochemical analysis of mouse spleen tissue, labeling TIL/TLR1 with ab195439 at 10 µg/ml.

References

ab195439 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab195439.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up