Overview

  • Product name

    Tinidazole, Antiprotozoal agent
  • Description

    Synthetic imidazole derivative. Antiprotozoal agent.
  • Biological description

    Synthetic imidazole derivative. Antiprotozoal agent. Metronidazole (ab141287) analog. Generates free nitro radicals. Induces DNA damage. Shows antiprotozoal and antibiotic effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    19387-91-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-(2-ethylsulfonylethyl)-2-methyl-5-nitroimidazole
  • Molecular weight

    247.27
  • Molecular formula

    C8H13N3O4S
  • PubChem identifier

    5479
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCS(=O)(=O)CCN1C(=NC=C1[N+](=O)[O-])C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Wu L  et al. Development of a HPLC/MS/MS method for simultaneous determination of tinidazole, dyclonine and chlorhexidine in rat plasma and its application in the pharmacokinetic research of a film-forming solution. J Pharm Biomed Anal 62:224-7 (2012). Read more (PubMed: 22305084) »
  • Deyab FA  et al. Effect of organochlorine (DDT) exposure on experimental giardiasis. J Egypt Soc Parasitol 38:225-41 (2008). Read more (PubMed: 19143133) »
  • Leal-Garza CH  et al. Tinidazole and emetine cytogenetic effects evaluated by the micronucleus test in mice. Arch Invest Med (Mex) 15:311-6 (0). Read more (PubMed: 6535518) »

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