Tiopronin (Thiola), Short acting reducing agent (ab145677)

Overview

  • Product name

    Tiopronin (Thiola), Short acting reducing agent
  • Description

    Short acting reducing agent
  • Alternative names

    • Thiola
  • Biological description

    Short acting reducing agent. Shows anticystinuric and hepatoprotective effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    1953-02-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    2-(2-Sulfanylpropanoylamino)acetic acid
  • Molecular weight

    163.19
  • Molecular formula

    C5H9NO3S
  • PubChem identifier

    5483
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM, in ethanol to 100 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C(=O)NCC(=O)O)S
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Huo S  et al. Kinetics and mechanism of reactions of the drug tiopronin with platinum(IV) complexes. J Inorg Biochem 125:9-15 (2013). Read more (PubMed: 23665090) »
  • Prokopovich P  et al. A novel bone cement impregnated with silver-tiopronin nanoparticles: its antimicrobial, cytotoxic, and mechanical properties. Int J Nanomedicine 8:2227-37 (2013). Read more (PubMed: 23818779) »
  • Wang JQ  et al. Protective effects of tiopronin against high fat diet-induced non-alcoholic steatohepatitis in rats. Acta Pharmacol Sin 33:791-7 (2012). Read more (PubMed: 22543705) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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