Product nameAnti-Tissue kallikrein antibody
See all Tissue kallikrein primary antibodies
DescriptionMouse polyclonal to Tissue kallikrein
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Baboon, Cynomolgus monkey
Full length protein corresponding to Human Tissue kallikrein aa 1-262.
MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQC GGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPG FNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPTEEPEVG STCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCV GHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSY VKWIEDTIAENS
Database link: NP_002248.1
- IHC-P: Human salivary gland tissue. WB: Tissue kallikrein transfected 293T cell line.
Protein previously labeled as Kallikrein 1.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.20
Constituent: 100% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab169291 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 29 kDa.|
|IHC-P||Use a concentration of 3 µg/ml.|
FunctionGlandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Tissue specificityIsoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.
Sequence similaritiesBelongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain.
modificationsThe O-linked polysaccharides on Ser-93, Ser-104 and Ser-167 are probably the mucin type linked to GalNAc. In PubMed:3163150, GalNAc was detected with the corresponding peptides but not located.
- Information by UniProt
- Glandular kallikrein 1 antibody
- hK 1 antibody
- hK1 antibody
Immunohistochemical analysis of formalin-fixed paraffin-embedded Human salivary gland tissue, labelling Tissue kallikrein with ab169291 at 3 µg/ml.
All lanes : Anti-Tissue kallikrein antibody (ab169291) at 1 µg/ml
Lane 1 : Tissue kallikrein transfected 293T lysate
Lane 2 : Non-transfected 293T lysate
Lysates/proteins at 15 µl per lane.
Predicted band size: 29 kDa
ab169291 has not yet been referenced specifically in any publications.