Overview

  • Product name

  • Description

    Rabbit polyclonal to TL1A
  • Host species

    Rabbit
  • Specificity

    Detects endogenous levels of total TL1A protein.
  • Tested applications

    Suitable for: WB, ICC/IF, ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide C-terminal of human TNFSF15.

  • Positive control

    • COLO205 cell extract HeLa cells

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol, 0.87% Sodium chloride

    Without Mg2+ and Ca2+
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab64986 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).
ICC/IF 1/500 - 1/1000.
ELISA 1/20000.

Target

  • Function

    Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
  • Tissue specificity

    Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
  • Sequence similarities

    Belongs to the tumor necrosis factor family.
  • Cellular localization

    Secreted and Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • MGC129934 antibody
    • MGC129935 antibody
    • TL1 A antibody
    • tl1 antibody
    • tl1a antibody
    • tnf ligand related molecule 1 antibody
    • TNF ligand-related molecule 1 antibody
    • tnf superfamily ligand tl1a antibody
    • TNF15_HUMAN antibody
    • TNFSF15 antibody
    • Tumor necrosis factor (ligand) superfamily member 15 antibody
    • Tumor necrosis factor ligand superfamily member 15 antibody
    • Tumor necrosis factor ligand superfamily member 15, secreted form antibody
    • Vascular endothelial cell growth inhibitor antibody
    • Vascular endothelial growth inhibitor 192a antibody
    • Vascular endothelial growth inhibitor antibody
    • vegi antibody
    • VEGI192A antibody
    see all

Images

  • All lanes : Anti-TL1A antibody (ab64986) at 1/500 dilution

    Lane 1 : COLO205 cell extract
    Lane 2 : COLO205 cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 20 kDa
    Observed band size: 20 kDa

  • Immunofluorescence analysis of HeLa cells, using ab64986 at 1/500-1/1000 dilution. Right hand panel was also treated with immunising peptide.

References

This product has been referenced in:

  • Xu W  et al. Transcriptome Sequencing Identifies Novel Immune Response Genes Highly Related to the Severity of Human Adenovirus Type 55 Infection. Front Microbiol 10:130 (2019). Read more (PubMed: 30787914) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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