Overview

  • Product name

  • Description

    Rabbit polyclonal to TL1A
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human TL1A (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • Positive control

    • Placenta tissue. PC-3 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab85566 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 20 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function

    Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
  • Tissue specificity

    Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
  • Sequence similarities

    Belongs to the tumor necrosis factor family.
  • Cellular localization

    Secreted and Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • MGC129934 antibody
    • MGC129935 antibody
    • TL1 A antibody
    • tl1 antibody
    • tl1a antibody
    • tnf ligand related molecule 1 antibody
    • TNF ligand-related molecule 1 antibody
    • tnf superfamily ligand tl1a antibody
    • TNF15_HUMAN antibody
    • TNFSF15 antibody
    • Tumor necrosis factor (ligand) superfamily member 15 antibody
    • Tumor necrosis factor ligand superfamily member 15 antibody
    • Tumor necrosis factor ligand superfamily member 15, secreted form antibody
    • Vascular endothelial cell growth inhibitor antibody
    • Vascular endothelial growth inhibitor 192a antibody
    • Vascular endothelial growth inhibitor antibody
    • vegi antibody
    • VEGI192A antibody
    see all

Images

  • Immunohistochemical staining of paraffin embedded, formalin fixed, human kidney tubules using ab85566 at 5 µg/mL.

  • Negative control - immunohistochemical staining of paraffin embedded, formalin fixed, human prostate using ab85566 at 5 µg/mL.

  • Lane 1 : Anti-TL1A antibody (ab85566) at 0.5 µg/ml
    Lane 2 : Anti-TL1A antibody (ab85566) at 1 µg/ml
    Lane 3 : Anti-TL1A antibody (ab85566) at 2 µg/ml

    All lanes : PC-3 cell lysate

    Predicted band size: 20 kDa
    Observed band size: 25 kDa
    why is the actual band size different from the predicted?

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue, staining TL1A with ab85566 at 5 µg/ml.

References

This product has been referenced in:

  • Zhang ZH  et al. Changes in TL1A levels and associated cytokines during pathogenesis of diabetic retinopathy. Mol Med Rep 15:573-580 (2017). Read more (PubMed: 28000874) »
See 1 Publication for this product

Customer reviews and Q&As

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