Key features and details
- Rabbit polyclonal to TL1A
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-TL1A antibody
See all TL1A primary antibodies
DescriptionRabbit polyclonal to TL1A
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human TL1A (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityIon Exchange Chromatography
Our Abpromise guarantee covers the use of ab85566 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 20 kDa.|
|IHC-P||Use a concentration of 5 µg/ml.|
FunctionReceptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
Tissue specificitySpecifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
Sequence similaritiesBelongs to the tumor necrosis factor family.
Cellular localizationSecreted and Membrane.
- Information by UniProt
- MGC129934 antibody
- MGC129935 antibody
- TL1 A antibody
Immunohistochemical staining of paraffin embedded, formalin fixed, human kidney tubules using ab85566 at 5 µg/mL.
Negative control - immunohistochemical staining of paraffin embedded, formalin fixed, human prostate using ab85566 at 5 µg/mL.
Lane 1 : Anti-TL1A antibody (ab85566) at 0.5 µg/ml
Lane 2 : Anti-TL1A antibody (ab85566) at 1 µg/ml
Lane 3 : Anti-TL1A antibody (ab85566) at 2 µg/ml
All lanes : PC-3 cell lysate
Predicted band size: 20 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue, staining TL1A with ab85566 at 5 µg/ml.
ab85566 has been referenced in 2 publications.
- Kumanishi S et al. Epigenetic modulators hydralazine and sodium valproate act synergistically in VEGI-mediated anti-angiogenesis and VEGF interference in human osteosarcoma and vascular endothelial cells. Int J Oncol 55:167-178 (2019). PubMed: 31180533
- Zhang ZH et al. Changes in TL1A levels and associated cytokines during pathogenesis of diabetic retinopathy. Mol Med Rep 15:573-580 (2017). PubMed: 28000874