Recombinant

Recombinant Anti-TL1A antibody [VEGI/2052R] - BSA and Azide free (ab236303)

Overview

  • Product name

    Anti-TL1A antibody [VEGI/2052R] - BSA and Azide free
    See all TL1A primary antibodies
  • Description

    Rabbit monoclonal [VEGI/2052R] to TL1A - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Protein Array, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human TL1A.
    Database link: O95150

  • Positive control

    • IHC-P: Human colon carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab236303 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Protein Array Use at an assay dependent concentration.
IHC-P Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Primary incubation for 30 minutes at room temperature.

Target

  • Function

    Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.
  • Tissue specificity

    Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
  • Sequence similarities

    Belongs to the tumor necrosis factor family.
  • Cellular localization

    Secreted and Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • MGC129934 antibody
    • MGC129935 antibody
    • TL1 A antibody
    • tl1 antibody
    • tl1a antibody
    • tnf ligand related molecule 1 antibody
    • TNF ligand-related molecule 1 antibody
    • tnf superfamily ligand tl1a antibody
    • TNF15_HUMAN antibody
    • TNFSF15 antibody
    • Tumor necrosis factor (ligand) superfamily member 15 antibody
    • Tumor necrosis factor ligand superfamily member 15 antibody
    • Tumor necrosis factor ligand superfamily member 15, secreted form antibody
    • Vascular endothelial cell growth inhibitor antibody
    • Vascular endothelial growth inhibitor 192a antibody
    • Vascular endothelial growth inhibitor antibody
    • vegi antibody
    • VEGI192A antibody
    see all

Images

  • This data was produced with ab234307, the same antibody in a different formulation with BSA and Azide.
    ab234307 was tested in protein array against over 19000 different full-length human proteins.
    Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
    A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
  • Fomalin-fixed, paraffin-embedded human colon carcinoma tissue stained for TL1A using ab234307 at 2 μg/ml in immunohistochemical analysis.

    This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA and sodium azide (ab234307).

References

ab236303 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab236303.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up