Key features and details
- Mouse monoclonal [4H8C1] to TLL1
- Suitable for: WB, Flow Cyt
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-TLL1 antibody [4H8C1]
See all TLL1 primary antibodies
DescriptionMouse monoclonal [4H8C1] to TLL1
Tested applicationsSuitable for: WB, Flow Cytmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
- WB: Recombinant human TLL1 (AA: 870-1013) protein; TLL1 (AA: 870-1013)-hIgGFc transfected HEK-293 whole cell lysate. Flow: HeLa cells.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab233827 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000.|
|Flow Cyt||1/200 - 1/400.|
FunctionProtease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.
Involvement in diseaseDefects in TLL1 are the cause of atrial septal defect type 6 (ASD6) [MIM:613087]. A congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria.
Sequence similaritiesBelongs to the peptidase M12A family.
Contains 5 CUB domains.
Contains 2 EGF-like domains.
- Information by UniProt
- ASD6 antibody
- TLL antibody
- TLL1 antibody
Anti-TLL1 antibody [4H8C1] (ab233827) at 1/500 dilution + Recombinant human TLL1 (AA: 870-1013)
Developed using the ECL technique.
Expected MW is 42.2
All lanes : Anti-TLL1 antibody [4H8C1] (ab233827)
Lane 1 : HEK-293 (human epithelial cell line from embryonic kidney) whole cell lysate
Lane 2 : TLL1 (AA: 870-1013)-hIgGFc transfected HEK-293 whole cell lysate
Developed using the ECL technique.
Flow cytometric analysis of HeLa (human epithelial cell line from cervix adenocarcinoma) cell line labeling TLL1 with ab233827 at 1/200 dilution (green) compared with a negative control (red).
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab233827 has not yet been referenced specifically in any publications.