Anti-TLL1 antibody (ab167664)

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Western blot - Anti-TLL1 antibody (ab167664)

    Key features and details

    • Mouse polyclonal to TLL1
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-TLL1 antibody
      See all TLL1 primary antibodies

    • Description

      Mouse polyclonal to TLL1

    • Host species

      Mouse

    • Specificity

      Detects Isoform 2 of O43897.

    • Tested applications

      Suitable for: WBmore details

    • Species reactivity

      Reacts with: Human

    • Immunogen

      Full length protein corresponding to Human TLL1 aa 1-392.
      Sequence:

      MGLGTLSPRMLVWLVASGIVFYGELWVCAGLDYDYTFDGNEEDKTETIDY KDPCKAAVFWGDIALDDEDLNIFQIDRTIDLTQNPFGNLGHTTGGLGDHA MSKKRGALYQLIDRIRRIGFGLEQNNTVKGKVPLQFSGQNEKNRVPRAAT SRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFIERSDEE SYIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWH EHTRPDRDNHVTIIRENIQPGQEYNFLKMEPGEVNSLGERYDFDSIMHYA RNTFSRGMFLDTILPSRDDNGIRPAIGQRTRLSKGDIAQARKLYRCPACG ETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKVVFSLC


      Database link: O43897-2
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • Positive control

      • TLL1 transfected 293T cell lysate.

    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    Applications

    Our Abpromise guarantee covers the use of ab167664 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa.

    Target

    • Function

      Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.

    • Involvement in disease

      Defects in TLL1 are the cause of atrial septal defect type 6 (ASD6) [MIM:613087]. A congenital heart malformation characterized by incomplete closure of the wall between the atria resulting in blood flow from the left to the right atria.

    • Sequence similarities

      Belongs to the peptidase M12A family.
      Contains 5 CUB domains.
      Contains 2 EGF-like domains.

    • Cellular localization

      Secreted.
    • Information by UniProt

    • Database links

      • Alternative names

        • ASD6 antibody
        • TLL antibody
        • TLL1 antibody
        • TLL1_HUMAN antibody
        • Tolloid like 1 antibody
        • Tolloid-like protein 1 antibody
        see all

      Images

      • Western blot - Anti-TLL1 antibody (ab167664)
        Western blot - Anti-TLL1 antibody (ab167664)
        All lanes : Anti-TLL1 antibody (ab167664) at 1 µg/ml

        Lane 1 : TLL1 transfected 293T cell lysate

        Lane 2 : Non-transfected 293T cell lysate


        Lysates/proteins at 15 µl per lane.

        Predicted band size: 44 kDa
        Observed band size: 44 kDa

      References (0)

      Publishing research using ab167664? Please let us know so that we can cite the reference in this datasheet.

      ab167664 has not yet been referenced specifically in any publications.

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