Anti-TLR10 antibody [3C10C5] (ab113446)

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Key features and details

  • Mouse monoclonal [3C10C5] to TLR10
  • Reacts with: Human
  • Isotype: IgG1

Overview

  • Product name

    Anti-TLR10 antibody [3C10C5]
    See all TLR10 primary antibodies

  • Description

    Mouse monoclonal [3C10C5] to TLR10

  • Host species

    Mouse

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant fragment, corresponding to extracellular domain amino acids 20-474 of Human TLR10 (NP_001017388 ).

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

Target

  • Function

    Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

  • Tissue specificity

    Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.

  • Sequence similarities

    Belongs to the Toll-like receptor family.
    Contains 15 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • CD 290 antibody
      • CD 290 antigen antibody
      • CD290 antibody
      • CD290 antigen antibody
      • MGC104967 antibody
      • MGC126398 antibody
      • MGC126399 antibody
      • OTTHUMP00000158729 antibody
      • OTTHUMP00000218162 antibody
      • TLR10 antibody
      • TLR10_HUMAN antibody
      • Toll like receptor 10 antibody
      • Toll-like receptor 10 antibody
      • UNQ315/PRO358 antibody
      see all

    References (0)

    Publishing research using ab113446? Please let us know so that we can cite the reference in this datasheet.

    ab113446 has not yet been referenced specifically in any publications.

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