Anti-TLR10 antibody [3C10C5] (ab113446)
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Overview
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Product name
Anti-TLR10 antibody [3C10C5]
See all TLR10 primary antibodies -
Description
Mouse monoclonal [3C10C5] to TLR10 -
Host species
Mouse -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment, corresponding to extracellular domain amino acids 20-474 of Human TLR10 (NP_001017388 ).
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.05% BSA -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
3C10C5 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab113446 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use at an assay dependent concentration. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
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Target
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Function
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. -
Tissue specificity
Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines. -
Sequence similarities
Belongs to the Toll-like receptor family.
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 81793 Human
- Omim: 606270 Human
- SwissProt: Q9BXR5 Human
- Unigene: 120551 Human
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Alternative names
- CD 290 antibody
- CD 290 antigen antibody
- CD290 antibody
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Protocols
Datasheets and documents
References
ab113446 has not yet been referenced specifically in any publications.
