Overview

  • Product name
    Anti-TLR10 antibody
    See all TLR10 primary antibodies
  • Description
    Rabbit polyclonal to TLR10
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to 14 amino acids near the middle of TLR10 (Human).

  • Positive control
    • Human lymph node cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab21273 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 94 kDa.Can be blocked with Active human TLR10 peptide (ab39866).
ICC/IF Use a concentration of 20 µg/ml.

Target

  • Function
    Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • Tissue specificity
    Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.
  • Sequence similarities
    Belongs to the Toll-like receptor family.
    Contains 15 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 TIR domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • CD 290 antibody
      • CD 290 antigen antibody
      • CD290 antibody
      • CD290 antigen antibody
      • MGC104967 antibody
      • MGC126398 antibody
      • MGC126399 antibody
      • OTTHUMP00000158729 antibody
      • OTTHUMP00000218162 antibody
      • TLR10 antibody
      • TLR10_HUMAN antibody
      • Toll like receptor 10 antibody
      • Toll-like receptor 10 antibody
      • UNQ315/PRO358 antibody
      see all

    Images

    • Western blot - Anti-TLR10 antibody (ab21273)
      Western blot - Anti-TLR10 antibody (ab21273)
      Lane 1 : Anti-TLR10 antibody (ab21273) at 0.5 µg/ml
      Lane 2 : Anti-TLR10 antibody (ab21273) at 1 µg/ml

      All lanes : Human lymph node cell lysates

      Predicted band size: 94 kDa
      Observed band size: 75 kDa (why is the actual band size different from the predicted?)

    References

    ab21273 has not yet been referenced specifically in any publications.

    Publishing research using ab21273? Please let us know so that we can cite the reference in this datasheet.

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