Anti-TLR10 antibody (ab21273)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-TLR10 antibody
See all TLR10 primary antibodies -
DescriptionRabbit polyclonal to TLR10
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Host speciesRabbit
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Tested applicationsSuitable for: WB, ICC/IFmore details
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Species reactivityReacts with: Human
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Immunogen
Synthetic peptide corresponding to 14 amino acids near the middle of TLR10 (Human).
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Positive control
- Human lymph node cell lysate.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C.
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Storage bufferPreservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purification notesIon exchange chromatography.
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Immunizing Peptide (Blocking)
Applications
Our Abpromise guarantee covers the use of ab21273 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 94 kDa.Can be blocked with Active human TLR10 peptide (ab39866). | |
| ICC/IF | Use a concentration of 20 µg/ml. |
Target
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FunctionParticipates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
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Tissue specificityHighly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.
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Sequence similaritiesBelongs to the Toll-like receptor family.
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain. -
Cellular localizationMembrane.
- Information by UniProt
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Database links
- Entrez Gene: 81793 Human
- Omim: 606270 Human
- SwissProt: Q9BXR5 Human
- Unigene: 120551 Human
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Alternative names
- CD 290 antibody
- CD 290 antigen antibody
- CD290 antibody
see all
Images
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Western blot - Anti-TLR10 antibody (ab21273)Lane 1 : Anti-TLR10 antibody (ab21273) at 0.5 µg/ml
Lane 2 : Anti-TLR10 antibody (ab21273) at 1 µg/ml
All lanes : Human lymph node cell lysates
Predicted band size: 94 kDa
Observed band size: 75 kDa why is the actual band size different from the predicted?
Datasheets and documents
References
ab21273 has not yet been referenced specifically in any publications.
