Anti-TLR10 antibody (ab21273)
- Datasheet
- References
- Protocols
Overview
-
Product nameAnti-TLR10 antibody
See all TLR10 primary antibodies -
DescriptionRabbit polyclonal to TLR10
-
Host speciesRabbit
-
Tested applicationsSuitable for: WB, ICC/IFmore details
-
Species reactivityReacts with: Human
-
Immunogen
Synthetic peptide corresponding to 14 amino acids near the middle of TLR10 (Human).
-
Positive control
- Human lymph node cell lysate.
Properties
-
FormLiquid
-
Storage instructionsShipped at 4°C. Store at +4°C.
-
Storage bufferPreservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purification notesIon exchange chromatography.
-
ClonalityPolyclonal
-
IsotypeIgG
-
Research areas
Associated products
-
Compatible Secondaries
-
Immunizing Peptide (Blocking)
-
Isotype control
Applications
Our Abpromise guarantee covers the use of ab21273 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 94 kDa.Can be blocked with Active human TLR10 peptide (ab39866). | |
| ICC/IF | Use a concentration of 20 µg/ml. |
Target
-
FunctionParticipates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
-
Tissue specificityHighly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.
-
Sequence similaritiesBelongs to the Toll-like receptor family.
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain. -
Cellular localizationMembrane.
- Information by UniProt
-
Database links
- Entrez Gene: 81793 Human
- Omim: 606270 Human
- SwissProt: Q9BXR5 Human
- Unigene: 120551 Human
-
Alternative names
- CD 290 antibody
- CD 290 antigen antibody
- CD290 antibody
see all
Images
-
Western blot - Anti-TLR10 antibody (ab21273)Lane 1 : Anti-TLR10 antibody (ab21273) at 0.5 µg/ml
Lane 2 : Anti-TLR10 antibody (ab21273) at 1 µg/ml
All lanes : Human lymph node cell lysates
Predicted band size: 94 kDa
Observed band size: 75 kDa why is the actual band size different from the predicted?
Datasheets and documents
References
ab21273 has not yet been referenced specifically in any publications.
