- Datasheet
- Specific References
- Protocols
Overview
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Product nameAnti-TLR11 antibody
See all TLR11 primary antibodies -
DescriptionRabbit polyclonal to TLR11
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Host speciesRabbit
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Tested applicationsSuitable for: ICC/IF, WBmore details
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Species reactivityReacts with: Mouse
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Immunogen
Synthetic peptide (Mouse) corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11(GenBank accession no. NP_991388).
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Positive control
- RAW264.7 cell lysates.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C.
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Storage bufferPreservative: 0.02% Sodium Azide
Constituents: PBS -
Concentration information loading... -
PurityIon Exchange Chromatography
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Purification notesPurified by ion exchange chromatography
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Immunizing Peptide (Blocking)
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab24183 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF | Use a concentration of 10 µg/ml. | |
| WB | Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 105 kDa).Can be blocked with Active mouse TLR11 peptide (ab39868). |
Target
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RelevanceToll like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.
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Cellular localizationType I membrane protein
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Database links
- Entrez Gene: 239081 Mouse
- SwissProt: Q6R5P0 Mouse
- Unigene: 291512 Mouse
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Alternative names
- hgnc31753 antibody
- Toll like receptor 11 antibody
Images
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Western blot - Anti-TLR11 antibody (ab24183)Lane 1 : Anti-TLR11 antibody (ab24183) at 0.5 µg/ml
Lane 2 : Anti-TLR11 antibody (ab24183) at 1 µg/ml
Lane 3 : Anti-TLR11 antibody (ab24183) at 2 µg/ml
All lanes : RAW 264.7 cell lysate.
Predicted band size: 105 kDa
Observed band size: 95 kDa (why is the actual band size different from the predicted?) -
Immunocytochemistry/ Immunofluorescence - Anti-TLR11 antibody (ab24183)ab24183 at 10µg/ml staining of TLR11 in RAW264.7 cells by ICC/IF
References
ab24183 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"