Anti-TLR11 antibody (ab24183)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-TLR11 antibody
See all TLR11 primary antibodies -
Description
Rabbit polyclonal to TLR11 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Synthetic peptide (Mouse) corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11(GenBank accession no. NP_991388).
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Positive control
- RAW264.7 cell lysates.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Ion Exchange Chromatography -
Purification notes
Purified by ion exchange chromatography -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab24183 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF | Use a concentration of 10 µg/ml. | |
| WB | Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 105 kDa). |
Target
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Relevance
Toll like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system. -
Cellular localization
Type I membrane protein -
Database links
- Entrez Gene: 239081 Mouse
- SwissProt: Q6R5P0 Mouse
- Unigene: 291512 Mouse
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Alternative names
- hgnc31753 antibody
- Toll like receptor 11 antibody
Images
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Western blot - Anti-TLR11 antibody (ab24183)Lane 1 : Anti-TLR11 antibody (ab24183) at 0.5 µg/ml
Lane 2 : Anti-TLR11 antibody (ab24183) at 1 µg/ml
Lane 3 : Anti-TLR11 antibody (ab24183) at 2 µg/ml
All lanes : RAW 264.7 cell lysate.
Predicted band size: 105 kDa
Observed band size: 95 kDa why is the actual band size different from the predicted? -
Immunocytochemistry/ Immunofluorescence - Anti-TLR11 antibody (ab24183)ab24183 at 10µg/ml staining of TLR11 in RAW264.7 cells by ICC/IF
Datasheets and documents
References
ab24183 has not yet been referenced specifically in any publications.
