Overview

  • Product name

    Anti-TLT-1 antibody [EP15294]
    See all TLT-1 primary antibodies
  • Description

    Rabbit monoclonal [EP15294] to TLT-1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human TLT-1 aa 50-200. The exact sequence is proprietary.
    Database link: Q86YW5

  • Positive control

    • Human spleen tissue; Jurkat cells.
  • General notes

    Previously labelled as TREML1. 

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

Properties

Applications

Our Abpromise guarantee covers the use of ab192619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
ICC/IF 1/50.

Target

  • Function

    Cell surface receptor that may play a role in the innate and adaptive immune response.
  • Tissue specificity

    Detected in platelets, monocytic leukemia and in T-cell leukemia.
  • Sequence similarities

    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Post-translational
    modifications

    Phosphorylated on tyrosine residues.
  • Cellular localization

    Cell membrane. Cytoplasm. Sequestered in cytoplasmic vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis.
  • Information by UniProt
  • Database links

  • Alternative names

    • dJ238O23.3 antibody
    • GLTL1825 antibody
    • MGC119173 antibody
    • PRO3438 antibody
    • TLT 1 antibody
    • TLT-1 antibody
    • TLT1 antibody
    • TREM like transcript 1 antibody
    • Trem like transcript 1 protein antibody
    • Trem-like transcript 1 protein antibody
    • TREML 1 antibody
    • Treml1 antibody
    • Triggering receptor expressed on myeloid cells like 1 antibody
    • Triggering receptor expressed on myeloid cells like protein 1 antibody
    • Triggering receptor expressed on myeloid cells-like protein 1 antibody
    • TRML1_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human spleen tissue labeling TLT-1 with ab192619 at 1/1000 dilution (0.08μg/ml). A Ready to use HRP Polymer for Rabbit IgG (prediluted) was used as secondary. Counterstain: Hematoxylin.

    Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

  • Immunofluorescent analysis of Jurkat cells (4% Paraformaldehyde-fixed, 0.1% tritonX-100 permeabilized) labeling TLT-1 with ab192619 at 1/50 dilution (1.6 μg/ml). A Goat anti rabbit IgG (Alexa Fluor488) at 1/400 dilution (ab150077) was used as secondary antibody.  Counterstain: DAPI.

References

ab192619 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab192619.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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