Anti-TM2D1/BBP antibody (ab230876)
Key features and details
- Rabbit polyclonal to TM2D1/BBP
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-TM2D1/BBP antibody -
Description
Rabbit polyclonal to TM2D1/BBP -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Cow -
Immunogen
Synthetic peptide corresponding to Human TM2D1/BBP (internal sequence) conjugated to keyhole limpet haemocyanin.
Database link: Q9BX74 -
Positive control
- WB: MCF7 whole cell lysate; Mouse kidney lysate. IHC-P: Human testis and brain cortex tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.01% Sodium azide
Constituents: PBS, 30% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab230876 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/100.
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WB |
1/500 - 1/1000. Predicted molecular weight: 22 kDa.
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Notes |
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IHC-P
1/100. |
WB
1/500 - 1/1000. Predicted molecular weight: 22 kDa. |
Target
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Relevance
The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. -
Cellular localization
Membrane; Multi-pass membrane protein -
Database links
- Entrez Gene: 514249 Cow
- Entrez Gene: 83941 Human
- Entrez Gene: 94043 Mouse
- Omim: 610080 Human
- SwissProt: Q9BX74 Human
- SwissProt: Q99MB3 Mouse
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Alternative names
- BBP antibody
- Beta amyloid binding protein antibody
- hBBP antibody
see all
Images
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All lanes : Anti-TM2D1/BBP antibody (ab230876) at 1/500 dilution
Lane 1 : MCF7 (Human breast adenocarcinoma cell line) whole cell lysate
Lane 2 : Mouse kidney lysate
Predicted band size: 22 kDa -
Formalin-fixed, paraffin-embedded human testis tissue stained for TM2D1/BBP using ab230876 at 1/100 dilution in immunohistochemical analysis.
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Formalin-fixed, paraffin-embedded human brain cortex tissue stained for TM2D1/BBP using ab230876 at 1/100 dilution in immunohistochemical analysis.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab230876 has not yet been referenced specifically in any publications.