Key features and details
- Rabbit polyclonal to TMC6
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-TMC6 antibody
DescriptionRabbit polyclonal to TMC6
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
a 14 amino acid synthetic peptide from near the amino terminus of human TMC6.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab67325 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 90 kDa).|
|IHC-P||Use a concentration of 2.5 µg/ml.|
RelevanceDefects in TMC6 are a cause of epidermodysplasia verruciformis, a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions. TMC6 is expressed in placenta, prostate, testis, activated T-lymphocytes and lymphokine-activated killer (LAK) lymphocytes. There are four named isoforms.
Cellular localizationEndoplasmic reticulum membrane; Multi-pass membrane protein
- Epidermodysplasia verruciformis protein 1 antibody
- EV1 antibody
- EVER1 antibody
Lane 1 : Anti-TMC6 antibody (ab67325) at 1 µg/ml
Lane 2 : Anti-TMC6 antibody (ab67325) at 2 µg/ml
All lanes : A20 cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 90 kDa
Observed band size: 90 kDa
ab67325 at 2.5 µg/ml staining TMC6 in human spleen tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).
ab67325 has not yet been referenced specifically in any publications.