Anti-TMEM16B antibody (ab113443)
Key features and details
- Rabbit polyclonal to TMEM16B
- Suitable for: WB, IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-TMEM16B antibody
See all TMEM16B primary antibodies -
Description
Rabbit polyclonal to TMEM16B -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Rat, Human
Predicted to work with: Mouse
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Immunogen
Synthetic peptide from the N terminal region of Human TMEM16B, conjugated to KLH.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab113443 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 114 kDa.
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| IHC-P | (2) |
Use a concentration of 5 µg/ml.
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| Notes |
|---|
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 114 kDa. |
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IHC-P
Use a concentration of 5 µg/ml. |
Target
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Function
Acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. May mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina. -
Tissue specificity
Retina, especially in the photoreceptor synaptic terminals. -
Sequence similarities
Belongs to the anoctamin family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 57101 Human
- Entrez Gene: 243634 Mouse
- Omim: 610109 Human
- SwissProt: Q9NQ90 Human
- SwissProt: Q8CFW1 Mouse
- Unigene: 148970 Human
- Unigene: 333398 Mouse
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Alternative names
- Ano2 antibody
- ANO2_HUMAN antibody
- Anoctamin 2 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM16B antibody (ab113443)ab113443, at 5 µg/ml, staining TMEM16B in formalin fixed, paraffin embedded Human small intestine tissue by Immunohistochemistry.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM16B antibody (ab113443)ab113443, at 5 µg/ml, staining TMEM16B in formalin fixed, paraffin embedded Human spleen tissue by Immunohistochemistry. -
Western blot - Anti-TMEM16B antibody (ab113443)Lane 1 : Anti-TMEM16B antibody (ab113443) at 1 µg/ml
Lane 2 : Anti-TMEM16B antibody (ab113443) at 2 µg/ml
All lanes : Rat brain tissue lysate
Predicted band size: 114 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab113443 has not yet been referenced specifically in any publications.