Key features and details
- Rabbit polyclonal to TMEM59
- Suitable for: ICC/IF, WB, ICC
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TMEM59 antibody
See all TMEM59 primary antibodies
DescriptionRabbit polyclonal to TMEM59
SpecificityMultiple isoforms of TMEM59 are known to exist. This antibody is predicted to not cross-react with other TMEM family members.
Tested applicationsSuitable for: ICC/IF, WB, ICCmore details
Species reactivityReacts with: Human
A 16 amino acid peptide near amino terminus of Human TMEM59 (NP_004863)
- Human Kidney Tissue Lysate
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab105417 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 36 kDa.|
|ICC||Use a concentration of 2.5 µg/ml.|
FunctionModulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.
Sequence similaritiesBelongs to the TMEM59 family.
Cellular localizationGolgi apparatus membrane.
- Information by UniProt
- C1orf8 antibody
- HSPC001 antibody
- Liver membrane-bound protein antibody
All lanes : Anti-TMEM59 antibody (ab105417) at 1 µg/ml
Lane 1 : Human kidney tissue lysate
Lane 2 : Human kidney tissue lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 36 kDa
Immunofluorescence of TMEM59 in Human kidney tissue with ab105417 at 20 ug/mL.
Immunohistochemistry of TMEM59 in human kidney tissue with ab105417 at 2.5 µg/ml.
ab105417 has not yet been referenced specifically in any publications.