Key features and details
- Rabbit polyclonal to TMPRSS11D
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-TMPRSS11D antibody
See all TMPRSS11D primary antibodies
DescriptionRabbit polyclonal to TMPRSS11D
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Recombinant fragment, corresponding to a region within amino acids 152-348 of Human TMPRSS11D (UniProt O60235).
- HepG2 whole cell lysate (ab7900); Human breast carcinoma tissue
General notesStore undiluted.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab127031 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 46 kDa.|
|IHC-P||1/100 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
FunctionMay play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
Tissue specificityLocated in the cells of the submucosal serous glands of the bronchi and trachea.
Sequence similaritiesBelongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
Contains 1 SEA domain.
Cellular localizationSecreted. Activated by cleavage and secreted and Cell membrane. Activated by cleavage and secreted.
- Information by UniProt
- Airway trypsin like protease antibody
- Airway trypsin-like protease antibody
- HAT antibody
ab127031 has been referenced in 3 publications.
- Muytjens CMJ et al. Functional proteomic profiling reveals KLK13 and TMPRSS11D as active proteases in the lower female reproductive tract. F1000Res 7:1666 (2018). PubMed: 30647911
- Cao X et al. High TMPRSS11D protein expression predicts poor overall survival in non-small cell lung cancer. Oncotarget 8:12812-12819 (2017). PubMed: 28086212
- Duhaime MJ et al. Cell Surface Human Airway Trypsin-Like Protease Is Lost During Squamous Cell Carcinogenesis. J Cell Physiol 231:1476-83 (2016). PubMed: 26297835