Anti-TMPRSS4 antibody (ab150595)
Key features and details
- Rabbit polyclonal to TMPRSS4
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TMPRSS4 antibody
See all TMPRSS4 primary antibodies -
Description
Rabbit polyclonal to TMPRSS4 -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Horse, Dog, Chimpanzee, Monkey, Gorilla, Common marmoset, Orangutan -
Immunogen
Synthetic peptide, corresponding to 19 amino acids from an internal region of Human TMPRSS4 (NP_063947.1).
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Positive control
- Human small intestine and colon tissues.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab150595 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Probable protease. Seems to be capable of activating ENaC. -
Tissue specificity
High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract. -
Sequence similarities
Belongs to the peptidase S1 family.
Contains 1 LDL-receptor class A domain.
Contains 1 peptidase S1 domain.
Contains 1 SRCR domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 451581 Chimpanzee
- Entrez Gene: 100390415 Common marmoset
- Entrez Gene: 489387 Dog
- Entrez Gene: 101147411 Gorilla
- Entrez Gene: 100071190 Horse
- Entrez Gene: 56649 Human
- Entrez Gene: 100436934 Orangutan
- Omim: 606565 Human
see all -
Alternative names
- UNQ776/PRO1570 antibody
- CAPH2 antibody
- Channel-activating protease 2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab150595 has been referenced in 2 publications.
- Li XM et al. Overexpression of TMPRSS4 promotes tumor proliferation and aggressiveness in breast cancer. Int J Mol Med 39:927-935 (2017). PubMed: 28259959
- Zhao X et al. Hypoxia Induces Apoptosis through HIF-1aSignaling Pathway in Human Uterosacral Ligaments of Pelvic Organ Prolapse. Biomed Res Int 2017:8316094 (2017). PubMed: 29230415