Anti-TNF Receptor I antibody (ab19139)

ab19139 has been referenced in 74 publications.

• Tian H  et al. Chinese medicine CGA formula ameliorates liver fibrosis induced by carbon tetrachloride involving inhibition of hepatic apoptosis in rats. J Ethnopharmacol 232:227-235 (2019). PubMed: 30471378
• Xu M  et al. Activated TNF-a/RIPK3 signaling is involved in prolonged high fat diet-stimulated hepatic inflammation and lipid accumulation: inhibition by dietary fisetin intervention. Food Funct 10:1302-1316 (2019). PubMed: 30793717
• Yang WS  et al. Arginine vasopressin attenuates the effects of TNF-a in aortic endothelial cells by inducing ectodomain shedding of TNF receptor 1. Biochem Biophys Res Commun 511:780-786 (2019). PubMed: 30833075
• Erice C  et al. Regional Differences in the Contributions of TNF Reverse and Forward Signaling to the Establishment of Sympathetic Innervation. Dev Neurobiol 79:317-334 (2019). PubMed: 31004466
• Peltzer N  et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature 557:112-117 (2018). PubMed: 29695863
• Taraborrelli L  et al. LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L. Nat Commun 9:3910 (2018). PubMed: 30254289
• Xing J  et al. Role of TNF-a in Regulating the Exercise Pressor Reflex in Rats With Femoral Artery Occlusion. Front Physiol 9:1461 (2018). PubMed: 30374312
• Lindqvist LM  et al. Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion. Cell Death Differ 25:782-794 (2018). PubMed: 29229994
• Kong QQ  et al. Cumulus cell-released tumor necrosis factor (TNF)-a promotes post-ovulatory aging of mouse oocytes. Aging (Albany NY) 10:1745-1757 (2018). PubMed: 30048240
• Zhang C  et al. Activation of TNF-a/NF-?B axis enhances CRL4BDCAF11E3 ligase activity and regulates cell cycle progression in human osteosarcoma cells. Mol Oncol N/A:N/A (2018). WB . PubMed: 29377600
• Annibaldi A  et al. Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2. Mol Cell 69:566-580.e5 (2018). PubMed: 29452637
• Deyhimi P & Alishahi B Study of Extrinsic Apoptotic Pathway in Oral Pemphigus Vulgaris Using TNFR 1 and FasL Immunohistochemical Markers and TUNEL Technique. J Dent (Shiraz) 19:132-141 (2018). PubMed: 29854887
• Rashidi M  et al. Umbelliprenin shows antitumor, antiangiogenesis, antimetastatic, anti-inflammatory, and immunostimulatory activities in 4T1 tumor-bearing Balb/c mice. J Cell Physiol N/A:N/A (2018). PubMed: 29797576
• Lo CH  et al. An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors. SLAS Discov 22:950-961 (2017). PubMed: 28530838
• Yang WS  et al. Diosgenin, an Activator of 1,25D3-MARRS Receptor/ERp57, Attenuates the Effects of TNF-a by Causing ADAM10-Dependent Ectodomain Shedding of TNF Receptor 1. Cell Physiol Biochem 43:2434-2445 (2017). PubMed: 29073626
• Wen S  et al. Necroptosis is a key mediator of enterocytes loss in intestinal ischaemia/reperfusion injury. J Cell Mol Med 21:432-443 (2017). IF . PubMed: 27677535
• Wei R  et al. SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination. Genes Dev 31:1162-1176 (2017). PubMed: 28701375
• Jaco I  et al. MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death. Mol Cell 66:698-710.e5 (2017). Mouse . PubMed: 28506461
• Siemieniuch MJ  et al. Type of Inflammation Differentially Affects Expression of Interleukin 1ß and 6, Tumor Necrosis Factor-a and Toll-Like Receptors in Subclinical Endometritis in Mares. PLoS One 11:e0154934 (2016). PubMed: 27152525
• Huang B  et al. Renal Tumor Necrosis Factor a Contributes to Hypertension in Dahl Salt-Sensitive Rats. Sci Rep 6:21960 (2016). IHC ; Rat . PubMed: 26916681
• Lu H  et al. Oxymatrine Induces Liver Injury through JNK Signalling Pathway Mediated by TNF-a In Vivo. Basic Clin Pharmacol Toxicol 119:405-11 (2016). PubMed: 27097917
• Al-Lamki RS  et al. Tumor necrosis factor receptor 2-signaling in CD133-expressing cells in renal clear cell carcinoma. Oncotarget 7:24111-24 (2016). Human . PubMed: 26992212
• Feng H  et al. Involvement of Ubiquitin-Editing Protein A20 in Modulating Inflammation in Rat Cochlea Associated with Silver Nanoparticle-Induced CD68 Upregulation and TLR4 Activation. Nanoscale Res Lett 11:240 (2016). ICC/IF ; Rat . PubMed: 27142878
• Hazra S  et al. Experimental reduction of miR-92a mimics arterial aging. Exp Gerontol 83:165-70 (2016). PubMed: 27523918
• Mulay SR  et al. Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis. Nat Commun 7:10274 (2016). WB . PubMed: 26817517
• Dong Y  et al. Regulation of vascular endothelial growth factor-C by tumor necrosis factor-a in the conjunctiva and pterygium. Int J Mol Med 38:545-50 (2016). PubMed: 27314284
• Aghagolzadeh P  et al. Calcification of vascular smooth muscle cells is induced by secondary calciprotein particles and enhanced by tumor necrosis factor-a. Atherosclerosis 251:404-414 (2016). PubMed: 27289275
• Lewis AK  et al. Oxidation increases the strength of the methionine-aromatic interaction. Nat Chem Biol 12:860-6 (2016). PubMed: 27547920
• Yan K  et al. Polyinosinic-Polycytidylic Acid Perturbs Ovarian Functions Through Toll-Like Receptor 3-Mediated Tumor Necrosis Factor A Production in Female Mice. Biol Reprod 93:11 (2015). PubMed: 26040668
• Przygrodzka E  et al. Expression of factors associated with apoptosis in the porcine corpus luteum throughout the luteal phase of the estrous cycle and early pregnancy: their possible involvement in acquisition of luteolytic sensitivity. Theriogenology 83:535-45 (2015). PubMed: 25457680
• Yshii LM  et al. Suppression of MAPK attenuates neuronal cell death induced by activated glia-conditioned medium in alpha-synuclein overexpressing SH-SY5Y cells. J Neuroinflammation 12:193 (2015). ICC/IF ; Human . PubMed: 26502720
• Sano M  et al. The luteotrophic function of galectin-1 by binding to the glycans on vascular endothelial growth factor receptor-2 in bovine luteal cells. J Reprod Dev 61:439-48 (2015). WB ; Cow . PubMed: 26155753
• Qiu Q  et al. Time-Course of the Effects of QSYQ in Promoting Heart Function in Ameroid Constrictor-Induced Myocardial Ischemia Pigs. Evid Based Complement Alternat Med 2014:571076 (2014). WB ; Pig . PubMed: 24817898
• Weiterer S  et al. Tumor necrosis factor alpha induces a serotonin dependent early increase in ciliary beat frequency and epithelial transport velocity in murine tracheae. PLoS One 9:e91705 (2014). IHC-P ; Mouse . PubMed: 24626175
• Fujita H  et al. Mechanism underlying I?B kinase activation mediated by the linear ubiquitin chain assembly complex. Mol Cell Biol 34:1322-35 (2014). PubMed: 24469399
• Hashiba K  et al. Galectin-3 contributes to luteolysis by binding to Beta 1 integrin in the bovine corpus luteum. Biol Reprod 91:2 (2014). Cow . PubMed: 24855102
• Lee SM  et al. Circulating TNF receptors are significant prognostic biomarkers for idiopathic membranous nephropathy. PLoS One 9:e104354 (2014). IHC-P . PubMed: 25098821
• Rickard JA  et al. TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice. Elife 3:N/A (2014). PubMed: 25443632
• Wang JH  et al. CXCR6 deficiency attenuates pressure overload-induced monocytes migration and cardiac fibrosis through downregulating TNF-a-dependent MMP9 pathway. Int J Clin Exp Pathol 7:6514-23 (2014). PubMed: 25400729
• Weinberg MS  et al. Opposing actions of hippocampus TNFa receptors on limbic seizure susceptibility. Exp Neurol 247:429-37 (2013). PubMed: 23333565
• Wei SG  et al. Subfornical organ mediates sympathetic and hemodynamic responses to blood-borne proinflammatory cytokines. Hypertension 62:118-25 (2013). PubMed: 23670302
• Schwingshackl A  et al. Regulation of interleukin-6 secretion by the two-pore-domain potassium channel Trek-1 in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 304:L276-86 (2013). Mouse . PubMed: 23275623
• Kisiswa L  et al. TNFa reverse signaling promotes sympathetic axon growth and target innervation. Nat Neurosci 16:865-73 (2013). PubMed: 23749144
• Ali M  et al. Altering the sphingolipid acyl chain composition prevents LPS/GLN-mediated hepatic failure in mice by disrupting TNFR1 internalization. Cell Death Dis 4:e929 (2013). Mouse . PubMed: 24263103
• Moh MC  et al. Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling. FASEB J 27:2957-66 (2013). IF, Flow Cyt ; Human . PubMed: 23620528
• Han J  et al. Nuclear expression of ß-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells. Mol Cancer Res 11:207-18 (2013). PubMed: 23339186
• He P  et al. Genetic deletion of TNF receptor suppresses excitatory synaptic transmission via reducing AMPA receptor synaptic localization in cortical neurons. FASEB J 26:334-45 (2012). PubMed: 21982949
• Lu P  et al. Critical role of TNF-a-induced macrophage VEGF and iNOS production in the experimental corneal neovascularization. Invest Ophthalmol Vis Sci 53:3516-26 (2012). PubMed: 22570350
• Bhattacharjee R  et al. cAMP prevents TNF-induced apoptosis through inhibiting DISC complex formation in rat hepatocytes. Biochem Biophys Res Commun 423:85-90 (2012). Rat . PubMed: 22634003
• Hosono K  et al. Increased tumor necrosis factor receptor 1 expression in human colorectal adenomas. World J Gastroenterol 18:5360-8 (2012). IHC-P ; Human . PubMed: 23082052
• Castillo A  et al. Tumor necrosis factor-a receptor type 1, not type 2, mediates its acute responses in the kidney. Am J Physiol Renal Physiol 302:F1650-7 (2012). PubMed: 22461305
• Cöl Arslan S & Scheidereit C The Prevalence of TNFa-Induced Necrosis over Apoptosis Is Determined by TAK1-RIP1 Interplay. PLoS One 6:e26069 (2011). PubMed: 22016814
• Maddahi A  et al. The role of tumor necrosis factor-a and TNF-a receptors in cerebral arteries following cerebral ischemia in rat. J Neuroinflammation 8:107 (2011). IHC . PubMed: 21871121
• Sakumoto R  et al. Localization of gene and protein expressions of tumor necrosis factor-{alpha} and tumor necrosis factor receptor types I and II in the bovine corpus luteum during the estrous cycle. J Anim Sci 89:3040-7 (2011). PubMed: 21551345
• Carvalho-Sousa CE  et al. Molecular basis for defining the pineal gland and pinealocytes as targets for tumor necrosis factor. Front Endocrinol (Lausanne) 2:10 (2011). ICC, IHC . PubMed: 22654792
• Gerlach B  et al. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 471:591-6 (2011). PubMed: 21455173
• Kalakeche R  et al. Endotoxin uptake by s1 proximal tubular segment causes oxidative stress in the downstream s2 segment. J Am Soc Nephrol 22:1505-16 (2011). PubMed: 21784899
• Liu Z  et al. ST6Gal-I Regulates Macrophage Apoptosis via a2-6 Sialylation of the TNFR1 Death Receptor. J Biol Chem 286:39654-62 (2011). WB ; Mouse . PubMed: 21930713
• Fang X  et al. Perfluorononanoic acid-induced apoptosis in rat spleen involves oxidative stress and the activation of caspase-independent death pathway. Toxicology 267:54-9 (2010). WB ; Rat . PubMed: 19878704
• Petersen SL  et al. Overcoming cancer cell resistance to Smac mimetic induced apoptosis by modulating cIAP-2 expression. Proc Natl Acad Sci U S A : (2010). WB ; Human . PubMed: 20547836
• Jiang B  et al. Neuroinflammation in advanced canine glaucoma. Mol Vis 16:2092-108 (2010). IHC-P ; Dog . PubMed: 21042562
• Emblom-Callahan MC  et al. Genomic phenotype of non-cultured pulmonary fibroblasts in idiopathic pulmonary fibrosis. Genomics 96:134-45 (2010). WB ; Human . PubMed: 20451601
• Gesslein B  et al. Tumor necrosis factor and its receptors in the neuroretina and retinal vasculature after ischemia-reperfusion injury in the pig retina. Mol Vis 16:2317-27 (2010). PubMed: 21152396
• Sun B  et al. Sertoli cell-initiated testicular innate immune response through toll-like receptor-3 activation is negatively regulated by Tyro3, Axl, and mer receptors. Endocrinology 151:2886-97 (2010). PubMed: 20363878
• Sciorati C  et al. Necdin is expressed in cachectic skeletal muscle to protect fibers from tumor-induced wasting. J Cell Sci 122:1119-25 (2009). Flow Cyt ; Mouse . PubMed: 19339547
• Marzetti E  et al. Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction. Mech Ageing Dev 130:272-80 (2009). WB ; Rat . PubMed: 19396981
• Vince JE  et al. TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis. J Biol Chem 284:35906-15 (2009). WB ; Mouse . PubMed: 19815541
• Marzetti E  et al. Effects of short-term GH supplementation and treadmill exercise training on physical performance and skeletal muscle apoptosis in old rats. Am J Physiol Regul Integr Comp Physiol 294:R558-67 (2008). PubMed: 18003794
• Khan AA  et al. Tumor necrosis factor alpha enhances the sensitivity of rat trigeminal neurons to capsaicin. Neuroscience 155:503-9 (2008). PubMed: 18582539
• Mahoney DJ  et al. Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation. Proc Natl Acad Sci U S A 105:11778-83 (2008). WB ; Mouse . PubMed: 18697935
• Gray-Schopfer VC  et al. Tumor necrosis factor-alpha blocks apoptosis in melanoma cells when BRAF signaling is inhibited. Cancer Res 67:122-9 (2007). PubMed: 17210691
• Harrison ML  et al. Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose. J Clin Oncol 25:4542-9 (2007). PubMed: 17925549
• Petersen SL  et al. Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. Cancer Cell 12:445-56 (2007). PubMed: 17996648
• Prudente A  et al. Host inflammatory response to polypropylene implants: insights from a quantitative immunohistochemical and birefringence analysis in a rat subcutaneous model. Int Braz J Urol 42:585-93 (0). IHC . PubMed: 27286125