Overview

  • Product name

    Anti-TNFRSF14/HVEM antibody
    See all TNFRSF14/HVEM primary antibodies
  • Description

    Rabbit polyclonal to TNFRSF14/HVEM
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IF, ICCmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human TNFRSF14/HVEM (C terminal).

  • Positive control

    • Raji cell lysate. Raji cells.
  • General notes

     This product was previously labelled as TNFRSF14

     

Properties

Applications

Our Abpromise guarantee covers the use of ab62462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 31 kDa).
ICC/IF Use a concentration of 20 µg/ml.
ICC Use a concentration of 10 µg/ml.

Target

  • Function

    Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
  • Tissue specificity

    Widely expressed, with the highest expression in lung, spleen and thymus.
  • Sequence similarities

    Contains 3 TNFR-Cys repeats.
  • Post-translational
    modifications

    N-glycosylated.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • HVEML antibody
    • ATAR antibody
    • CD270 antibody
    • CD40 like protein precursor antibody
    • Herpes virus entry mediator A antibody
    • Herpesvirus entry mediator A antibody
    • Herpesvirus entry mediator antibody
    • Herpesvirus entry mediator ligand antibody
    • HveA antibody
    • HVEM antibody
    • HVEM L antibody
    • LIGHT antibody
    • LIGHTR antibody
    • TNFRSF14 antibody
    • TNFSF 14 antibody
    • TNR14_HUMAN antibody
    • TR2 antibody
    • Tumor necrosis factor receptor like gene2 antibody
    • Tumor necrosis factor receptor superfamily member 14 antibody
    • Tumor necrosis factor receptor superfamily member 14 precursor antibody
    • Tumor necrosis factor receptor-like 2 antibody
    see all

Images

  • All lanes : Anti-TNFRSF14/HVEM antibody (ab62462) at 2 µg/ml

    Lane 1 : Raji cell lysate with no blocking peptide
    Lane 2 : Raji cell lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 31 kDa
    Observed band size: 27 kDa
    why is the actual band size different from the predicted?

  • Immunocytochemistry of TNFRSF14/HVEM in Raji cells with ab62462 antibody at 10 µg/ml.

  • Immunofluorescence of TNFRSF14/HVEM in Raji cells using ab62462 at 20 ug/ml.

References

ab62462 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab62462.
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