Anti-TNFRSF19L antibody (ab96220)
Key features and details
- Rabbit polyclonal to TNFRSF19L
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-TNFRSF19L antibody
See all TNFRSF19L primary antibodies -
Description
Rabbit polyclonal to TNFRSF19L -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 35-366 of Human TNFRSF19L (NP_116260)
-
Positive control
- 293T, A431, H1299, HepG2, MOLT4 and Raji cell lysate. HeLaS3 whole cell lysate. U87 xenograft tissue.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96220 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 46 kDa.
|
|
IHC-P |
1/100 - 1/500.
|
Notes |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 46 kDa. |
IHC-P
1/100 - 1/500. |
Target
-
Function
Mediates activation of NF-kappa-B. May play a role in T-cell activation. -
Tissue specificity
Highest levels are in spleen, lymph node, thymus, peripheral blood leukocytes, bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in brain, kidney and pancreas. -
Sequence similarities
Belongs to the RELT family.
Contains 1 TNFR-Cys repeat. -
Post-translational
modificationsPhosphorylated in vitro by OXSR1. -
Cellular localization
Cell membrane. Cytoplasm. - Information by UniProt
-
Database links
- Entrez Gene: 84957 Human
- Entrez Gene: 320100 Mouse
- Entrez Gene: 361615 Rat
- Omim: 611211 Human
- SwissProt: Q969Z4 Human
- SwissProt: Q8BX43 Mouse
- Unigene: 533720 Human
- Unigene: 40336 Mouse
-
Alternative names
- Receptor expressed in lymphoid tissues antibody
- Relt antibody
- TNFRSF19L antibody
see all
Images
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (3)
ab96220 has been referenced in 3 publications.
- Huang K et al. Construction and validation of a glioblastoma prognostic model based on immune-related genes. Front Neurol 13:902402 (2022). PubMed: 35968275
- Yao W et al. RELT promotes the growth of esophageal squamous cell carcinoma by activating the NF-?B pathway. Cell Cycle 20:1231-1241 (2021). PubMed: 34121605
- Cusick JK et al. RELT stains prominently in B-cell lymphomas and binds the hematopoietic transcription factor MDFIC. Biochem Biophys Rep 24:100868 (2020). PubMed: 33367115