Overview

  • Product name
    Anti-TNFSF18 / GITRL antibody
    See all TNFSF18 / GITRL primary antibodies
  • Description
    Rabbit polyclonal to TNFSF18 / GITRL
  • Host species
    Rabbit
  • Specificity
    ab25948 recognises GITRL.
  • Tested applications
    Suitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant full length protein corresponding to Human TNFSF18/ GITRL. Purified.

  • Positive control
    • WB: THP-1 cell lysate.
  • General notes

    Protein previously known as TNFSF18.

Properties

Applications

Our Abpromise guarantee covers the use of ab25948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 1 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 20 kDa).

Target

  • Function
    Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues.
  • Tissue specificity
    Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.
  • Sequence similarities
    Belongs to the tumor necrosis factor family.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activation inducible TNF related ligand antibody
    • Activation-inducible TNF-related ligand antibody
    • AITR ligand antibody
    • AITRL antibody
    • GITR ligand antibody
    • GITRL antibody
    • Glucocorticoid induced TNF related ligand antibody
    • Glucocorticoid induced TNFR related protein ligand antibody
    • Glucocorticoid-induced TNF-related ligand antibody
    • hGITRL antibody
    • MGC138237 antibody
    • TL6 antibody
    • TNF18_HUMAN antibody
    • TNFSF18 antibody
    • TNLG2A antibody
    • Tumor necrosis factor (ligand) superfamily member 18 antibody
    • Tumor necrosis factor ligand 2A antibody
    • Tumor necrosis factor ligand superfamily member 18 antibody
    see all

Images

  • All lanes : Anti-TNFSF18 / GITRL antibody (ab25948) at 1 µg/ml

    Lane 1 : 5 ng of purified recombinant TNFSF18 / GITRL
    Lane 2 : 25 ng of purified recombinant TNFSF18 / GITRL
    Lane 3 : 50 ng of purified recombinant TNFSF18 / GITRL

    Predicted band size: 20 kDa

  • ab25948 at 10 µg/ml staining TNFSF18 / GITRL in THP-1 cells by ICC/IF.

References

ab25948 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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