Anti-TNFSF18/GITRL antibody (ab25948)
Key features and details
- Rabbit polyclonal to TNFSF18/GITRL
- Suitable for: ICC/IF, WB
- Reacts with: Human, Recombinant fragment
- Isotype: IgG
Overview
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Product name
Anti-TNFSF18/GITRL antibody
See all TNFSF18/GITRL primary antibodies -
Description
Rabbit polyclonal to TNFSF18/GITRL -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, WBmore details -
Species reactivity
Reacts with: Human, Recombinant fragment -
Immunogen
Recombinant full length protein corresponding to Human TNFSF18/GITRL. Purified.
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Positive control
- WB: THP-1 cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab25948 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF |
Use a concentration of 10 µg/ml.
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| WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 20 kDa).
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| Notes |
|---|
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ICC/IF
Use a concentration of 10 µg/ml. |
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WB
Use a concentration of 1 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 20 kDa). |
Target
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Function
Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. -
Tissue specificity
Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. -
Sequence similarities
Belongs to the tumor necrosis factor family. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 8995 Human
- Omim: 603898 Human
- SwissProt: Q9UNG2 Human
- Unigene: 248197 Human
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Alternative names
- Activation inducible TNF related ligand antibody
- Activation-inducible TNF-related ligand antibody
- AITR ligand antibody
see all
Images
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Western blot - Anti-TNFSF18/GITRL antibody (ab25948)All lanes : Anti-TNFSF18/GITRL antibody (ab25948) at 1 µg/ml
Lane 1 : 5 ng of purified recombinant TNFSF18/GITRL
Lane 2 : 25 ng of purified recombinant TNFSF18/GITRL
Lane 3 : 50 ng of purified recombinant TNFSF18/GITRL
Predicted band size: 20 kDa -
Immunocytochemistry/ Immunofluorescence - Anti-TNFSF18/GITRL antibody (ab25948)ab25948 at 10 µg/ml staining TNFSF18/GITRL in THP-1 cells by ICC/IF.
Protocols
Datasheets and documents
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Datasheet download
References (1)
ab25948 has been referenced in 1 publication.
- Gao J et al. The involvement of protein TNFSF18 in promoting p-STAT1 phosphorylation to induce coronary microcirculation disturbance in atherosclerotic mouse model. Drug Dev Res 82:115-122 (2021). PubMed: 32820830
