Overview

  • Product name

    Anti-TNNT3 antibody [T1/61]
    See all TNNT3 primary antibodies
  • Description

    Mouse monoclonal [T1/61] to TNNT3
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, ELISA, IHC-P, IHC-Frmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chicken
  • Immunogen

    Full length native TNNT3 protein purified from Chicken breast muscle.

  • Positive control

    • Human skeletal muscle tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Clonality

    Monoclonal
  • Clone number

    T1/61
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab118886 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 31 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IHC-Fr Use at an assay dependent concentration.

Target

  • Function

    Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
  • Tissue specificity

    In fetal and adult fast skeletal muscles, with a higher level expression in fetal than in adult muscle.
  • Involvement in disease

    Defects in TNNT3 are a cause of distal arthrogryposis type 2B (DA2B) [MIM:601680]; also known as arthrogryposis multiplex congenita, distal, type 2B (AMCD2B). DA2B is a form of inherited multiple congenital contractures. Affected individuals have vertical talus, ulnar deviation in the hands, severe camptodactyly, and a distinctive face characterized by a triangular shape, prominent nasolabial folds, small mouth and a prominent chin.
  • Sequence similarities

    Belongs to the troponin T family.
  • Information by UniProt
  • Database links

  • Alternative names

    • AMCD2B antibody
    • Beta TnTF antibody
    • Beta-TnTF antibody
    • DA2B antibody
    • DKFZp779M2348 antibody
    • fast skeletal muscle antibody
    • Fast skeletal muscle troponin T antibody
    • FSSV antibody
    • fTnT antibody
    • TNNT 3 antibody
    • Tnnt3 antibody
    • TNNT3_HUMAN antibody
    • TnTf antibody
    • Troponin T antibody
    • Troponin T fast skeletal muscle antibody
    • Troponin T type 3 (skeletal fast) antibody
    • Troponin T type 3 antibody
    • Troponin T3 skeletal fast antibody
    see all

Images

  • ab118886, at 10 µg/ml, staining TNNT3 in Formalin-fixed, Paraffin-embedded Human Skeletal muscle tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab118886 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab118886.
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