Overview

  • Product name

    Anti-TNS4/CTEN antibody [EPR13792]
    See all TNS4/CTEN primary antibodies
  • Description

    Rabbit monoclonal [EPR13792] to TNS4/CTEN
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human TNS4/CTEN aa 200-300. The exact sequence is proprietary.
    Database link: Q8IZW8

  • Positive control

    • HeLA, HepG2, MCF-7, C6, Raw264.7, PC-12 and NIH/3T3 cell lysates.
  • General notes

     

     

     This product was previously labelled as TNS4

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab192247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 90 kDa (predicted molecular weight: 76 kDa).

Target

  • Function

    May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity). May promote apoptosis, via its cleavage by caspase-3.
  • Tissue specificity

    Prostate and placenta. Down regulated in prostate cancer.
  • Sequence similarities

    Contains 1 phosphatase tensin-type domain.
    Contains 1 SH2 domain.
  • Post-translational
    modifications

    Proteolytically cleaved by caspase-3 during apoptosis.
  • Cellular localization

    Cell junction > focal adhesion. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links

  • Alternative names

    • C terminal tensin like antibody
    • C terminal tensin like protein antibody
    • C-terminal tensin-like protein antibody
    • CTEN antibody
    • FLJ14950 antibody
    • PP14434 antibody
    • TENS4_HUMAN antibody
    • Tensin 4 antibody
    • Tensin-4 antibody
    • Tns4 antibody
    see all

Images

  • All lanes : Anti-TNS4/CTEN antibody [EPR13792] (ab192247) at 1/1000 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : HepG2 cell lysate
    Lane 3 : MCF-7 cell lysate

    Lysates/proteins at 20 µg per lane.

    Secondary
    All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 76 kDa
    Observed band size: 90 kDa
    why is the actual band size different from the predicted?



    Blocking/Dilution buffer: 5% NFDM /TBST.

  • All lanes : Anti-TNS4/CTEN antibody [EPR13792] (ab192247) at 1/1000 dilution

    Lane 1 : C6 cell lysate
    Lane 2 : Raw264.7 cell lysate
    Lane 3 : PC-12 cell lysate
    Lane 4 : NIH/3T3 cell lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

    Predicted band size: 76 kDa
    Observed band size: 90 kDa why is the actual band size different from the predicted?



    Blocking/Dilution buffer: 5% NFDM /TBST.

References

ab192247 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab192247.
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