Tolazoline hydrochloride, alpha-adrenoceptor antagonist (ab145762)

Overview

  • Product name

    Tolazoline hydrochloride, alpha-adrenoceptor antagonist
  • Description

    Non-selective, competitive α-adrenoceptor antagonist. Histamine H1 receptor agonist.
  • Biological description

    Non-selective, competitive α-adrenoceptor antagonist. Histamine H1 receptor agonist. Reverses drug-induced vasoconstriction and shows vasodilatory effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    59-97-2
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Casbeer HC & Knych HK Pharmacokinetics and pharmacodynamic effects of tolazoline following intravenous administration to horses. Vet J 196:504-9 (2013). Read more (PubMed: 23321455) »
  • Yokota S  et al. Effects of imidazoline and nonimidazoline alpha-adrenergic agents, including xylazine, medetomidine, yohimbine, tolazoline, and atipamezole, on aggregation of bovine and equine platelets. Am J Vet Res 74:395-402 (2013). Read more (PubMed: 23438114) »
  • Hubbell JA & Muir WW Antagonism of detomidine sedation in the horse using intravenous tolazoline or atipamezole. Equine Vet J 38:238-41 (2006). Read more (PubMed: 16706278) »

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