Anti-Topoisomerase II alpha antibody [Ki-S1] (ab139396)

Mouse monoclonal Topoisomerase II alpha antibody [Ki-S1]. Validated in IHC and tested in Human. Immunogen corresponding to tissue, cells or virus.

Overview

  • Product name

    Anti-Topoisomerase II alpha antibody [Ki-S1]
    See all Topoisomerase II alpha primary antibodies
  • Description

    Mouse monoclonal [Ki-S1] to Topoisomerase II alpha
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Cell preparation of Human histiocytic leukemia cell line U937.

  • Positive control

    • Human small intestine tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab139396 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50.

Target

  • Function

    Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
  • Sequence similarities

    Belongs to the type II topoisomerase family.
  • Post-translational
    modifications

    Phosphorylation has no effect on catalytic activity.
  • Cellular localization

    Cytoplasm. Nucleus > nucleoplasm. Generally located in the nucleoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • alpha isozyme antibody
    • ATP hydrolyzing DNA topoisomerase II alfa antibody
    • DNA gyrase antibody
    • DNA topoisomerase (ATP hydrolyzing) antibody
    • DNA topoisomerase 2 alpha antibody
    • DNA topoisomerase 2-alpha antibody
    • DNA topoisomerase II 170 kD antibody
    • DNA topoisomerase II alpha isozyme antibody
    • DNA topoisomerase II antibody
    • DNA Topoisomerase2 antibody
    • TOP 2A antibody
    • TOP2 antibody
    • TOP2A antibody
    • TOP2A_HUMAN antibody
    • Topoisomerase DNA II alpha 170kDa antibody
    • TP2A antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Human small intestine tissue labelled with ab139396 at 1/50 dilution.

References

ab139396 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab139396.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up