Key features and details
- Potent, selective IκB kinase inhibitor
- CAS Number: 507475-17-4
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameTPCA 1, IkappaB kinase inhibitor
DescriptionPotent, selective IκB kinase inhibitor
Potent, selective IκB kinase inhibitor (IC50 = 17.9 nM). Inhibits NF-κB nuclear localization. Shows anti-inflammatory effects in vivo.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab145522 has been referenced in 1 publication.
- Nakamura K et al. IFNT-independent effects of intrauterine extracellular vesicles (EVs) in cattle. Reproduction 159:503-511 (2020). PubMed: 32103820