Key features and details
- Metal ion chelator
- CAS Number: 16858-02-9
- Purity: > 99%
- Soluble in DMSO to 25 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameTPEN, Metal ion chelator
DescriptionMetal ion chelator
Metal ion chelator. Decreases intracellular zinc levels. Induces apoptosis. Causes defects in oocyte maturation. Modulates hippocampal neurogenesis following seizure. Cell permeable. Active in vivo and in vitro.
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 25 mM and in ethanol to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141111 has been referenced in 1 publication.
- Lee EJ et al. Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation. Nat Commun 6:7168 (2015). PubMed: 25981743