Overview

  • Product name

    TPh A, nuclear protein pirin inhibitor
  • Description

    Inhibitor of nuclear protein pirin
  • Alternative names

    • S-[p-(Benzyloxy)phenyl]-S-methyl-N-(p-tolylsulfonyl)-sulfilimine
  • Biological description

    Inhibitor of nuclear protein pirin. Inhibits the interaction between Bcl3 oncoprotein and pirin. Melanoma cell migration inhibitor.
  • Purity

    > 98%
  • CAS Number

    21306-65-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-Methyl-N-[methyl[4-(phenylmethoxy)phenyl]-λ4-sulfanylidene]-benzenesulfonamide
  • Molecular weight

    399.53
  • Molecular formula

    C21H21NO3S2
  • PubChem identifier

    9583267
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark.
  • Solubility overview

    Soluble in DMSO to 75 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=CC=C(C=C1)S(=O)(=O)/N=S(\C)/C2=CC=C(C=C2)OCC3=CC=CC=C3
  • Source

    Synthetic

References

This product has been referenced in:

  • Miyazaki I  et al. A small-molecule inhibitor shows that pirin regulates migration of melanoma cells. Nat Chem Biol 6:667-73 (2010). Read more (PubMed: 20711196) »
See 1 Publication for this product

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