Key features and details
- Rabbit polyclonal to TPN
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-TPN antibody
See all TPN primary antibodies
DescriptionRabbit polyclonal to TPN
Specificityab196764 detects endogenous level of total TPN protein.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human
Recombinant fragment within Human TPN (N terminal). The exact sequence is proprietary.
Database link: O15533
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 49% PBS
PBS without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab196764 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 48 kDa.|
FunctionInvolved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
Tissue specificityNeutrophils, mostly in fully differentiated cells.
Sequence similaritiesContains 1 Ig-like C1-type (immunoglobulin-like) domain.
DomainThe N-terminus is required for efficient association with MHC class I molecule and for a stable interaction between MHC I and calreticulin. Binding to TAP is mediated by the C-terminus region.
Cellular localizationEndoplasmic reticulum membrane.
- Information by UniProt
- NGS 17 antibody
- NGS-17 antibody
- NGS17 antibody
ab196764 has been referenced in 2 publications.
- Babaer D et al. Methylselenol producing selenocompounds enhance the efficiency of mammaglobin-A peptide vaccination against breast cancer cells. Oncol Lett 18:6891-6898 (2019). PubMed: 31807192
- Dellgren C et al. Low Constitutive Cell Surface Expression of HLA-B Is Caused by a Posttranslational Mechanism Involving Glu180 and Arg239. J Immunol 197:4807-4816 (2016). PubMed: 27821669