Product nameAnti-TR-1 antibody
DescriptionRabbit polyclonal to TR-1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to Human TR-1 aa 300 to the C-terminus conjugated to keyhole limpet haemocyanin.
(Peptide available as
- This antibody gave a positive signal in human adult and fetal heart tissue lysates.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab80878 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionMay inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.
Tissue specificityExpressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.
Sequence similaritiesBelongs to the tomoregulin family.
Contains 1 EGF-like domain.
Contains 2 Kazal-like domains.
Cellular localizationCell membrane.
- Information by UniProt
- C9orf2 antibody
- C9orf3 TMEFF1 antibody
- C9orf30 TMEFF1 antibody
All lanes : Anti-TR-1 antibody (ab80878) at 1/250 dilution
Lane 1 : Heart (Human) Whole Cell Lysate - fetal normal tissue
Lane 2 : Human heart tissue lysate - total protein (ab29431)
Lysates/proteins at 10 µg per lane.
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 41 kDa
Observed band size: 45 kDa why is the actual band size different from the predicted?
Additional bands at: 37 kDa (possible isoform)
Exposure time: 20 minutes
This antibody was raised against an immunogen that is predicted to cross react with both isoform 1 (41 kDa) and isoform 2 (37 kDa) of TR-1. We believe that the band observed at 37 kDa seen in lane 1 corresponds to isoform 2.
ab80878 has not yet been referenced specifically in any publications.